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Combination targeting of 'platelets + fibrin' enhances clot anchorage efficiency of nanoparticles for vascular drug delivery.

Nanoscale. 2020-11;

Sun M,Miyazawa K,Pendekanti T,Razmi A,Firlar E,Yang S,Shokuhfar T,Li O,Li W,Sen Gupta A

Products/Services Used	Details	Operation
Peptide Synthesis	For platelet binding peptide (PBP) the sequence CGSSSGRGDSPA that binds to activated platelet surface integrin αIIbβ334 was used, and for fibrin binding peptide (FBP), the sequence cyclo-AC-Y(DGI)C(HPr)YGLCYIQGK-Am35 was used. Both peptides were custom synthesized by Genscript (Piscataway, USA).	Get A Quote