| Products/Services Used | Details | Operation |
|---|---|---|
| Recombinant Antibody Expression | … plates were coated with recombinant RBD proteins (Genscript) from the 2019-nCoV strain or … Plates were coated with recombinant RBD proteins (Genscript) from the 2019-nCoV strain … | Get A Quote |
The SARS-CoV-2 Omicron variant has caused infections among individuals vaccinated or with prior COVID-19, suggesting immune escape. Here, we showed a decrease in binding and surrogate neutralizing antibody responses to the Omicron variant after two doses of the Pfizer COVID-19 mRNA vaccine. Individuals recovered from infection before vaccination had higher antibody levels and avidity to the Omicron variant compared to individuals vaccinated without infection. This suggested that COVID-19 infection before vaccination elicited a higher magnitude and affinity antibody response to the Omicron variant, and repeated exposure through infection or vaccine may be required to improve immunity to emerging SARS-CoV-2 varia... More
