Products/Services Used | Details | Operation |
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Catalog Antibody | … 2. Materials and methods. 2.1. Materials. RADARADARADARADA (Purity: >95%, GenScript Corporation, USA), PDGF-BB (≥98%, Sigma Aldrich, USA), Antibodies (Invitrogen, USA), microorganism (ATCC, USA) were the key materials used in the study … | Get A Quote |
Self assembling peptidebased hydrogel has been explored for delivering growth factors, anticancer drugs, antibiotics etc. Here, RADA 16-I (RADARADARADARADA), an ionic self complementary peptide that forms a well defined nanohydrogel has been studied for its ability to deliver PDGF-BB in a sustained manner and to destruct biofilm formed by wound specific pathogens. Results of the structural analysis of the nanohydrogel studied through AFM, FeSEM, CD, FT-IR and Rheometry, revealed the hydrogel forming ability of RADA 16-I with stable β-sheet structure at room temperature. The nanohydrogel was also found to destruct the biofilm formed under in vitro condition using S. aureus, E. coli and P. aeruginosa. The growth... More