| Products/Services Used | Details | Operation |
|---|---|---|
| Peptide Synthesis | … LA monomer was dried under vacuum at 40 °C for 24 h before use The osteogenic growth peptide (OGP) purchased from GenScript with the purity over 950% 22 Synthesis of Active Mesoporous Silica Nanoparticles The processes developed by Lai et al and Lee et al … | Get A Quote |
The manufacture of a biocompatible carrier for controlled delivery of bioactive compounds is described. This carrier is composed of a mesoporous silica nanoparticle as core that is homogenously distributed in an injectable hydrogel. For the synthesis of nanoparticles, a one step sol-gel method is developed to produce pores with the range of 100 nm. BMP2 and Fluorescein-conjugated bovine serum albumin is used as proteinaceous agents for measuring release, and is loaded into mesoporous silica nanoparticles at the optimum conditions of 48 h incubation period using 1:10 ratio of protein to nanoparticles. The release of proteins from either mesoporous nanoparticles or hydrogel individually involves a burst release ... More
