The efficient conjugation of a ruthenium complex and the peptide hormone somatostatin is presented. The resultant biohybrid offers valuable features for photodynamic therapy such as remarkable cellular selectivity， rapid cell uptake by receptor-mediated endocytosis， efficient generation of (1)O2 upon irradiation， potent phototoxicity as well as low cytotoxicity in the "off"-state.
The efficient conjugation of a ruthenium complex and the peptide hormone somatostatin is presented. The resultant biohybrid offers valuable features for photodynamic therapy such as remarkable cellular selectivity， rapid cell uptake by receptor-mediated endocytosis， efficient generation of (1)O2 upon irradiation， potent phototoxicity as well as low cytotoxicity in the "off"-state.
