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MiR-137 and miR-34a directly target Snail and inhibit EMT， invasion and sphere-forming ability of ovarian cancer cells.

J. Exp. Clin. Cancer Res.. 2016;

Dong Peixin，Xiong Ying，Watari Hidemichi，Hanley Sharon J B，Konno Yosuke，Ihira Kei，Yamada Takahiro，Kudo Masataka，Yue Junming，Sakuragi Nor

Products/Services Used	Details	Operation
Catalog Antibody	Equal amounts of protein lysates (30 μg) were separated by 10 % SDS -PAGE for immunoblots with antibodies to Snail (Abcam), E-cadherin (GenScript), N-cadherin (BD Biosciences), Vimentin (GenScript) and GAPDH (Santa Cruz).	Get A Quote

摘要

In ovarian cancer (OC) cells， Snail was reported to induce the epithelial-to-mesenchymal transition (EMT)， which is a critical step in OC metastasis. At present little is known about controlling Snail expression in OC cells by using specific microRNAs (miRNAs).