CD2-associated protein (CD2AP)， a slit diaphragm-associated scaffolding protein involved in survival and regulation of the cytoskeleton in podocytes， is considered a "stabilizer" of the slit diaphragm complex that connects the slit diaphragm protein nephrin to the cytoskeleton of the cell. Tyrosine phosphorylation of slit diaphragm molecules can influence their surface expression， but it is unknown whether tyrosine phosphorylation events of CD2AP are also physiologically relevant to slit diaphragm stability.
CD2-associated protein (CD2AP)， a slit diaphragm-associated scaffolding protein involved in survival and regulation of the cytoskeleton in podocytes， is considered a "stabilizer" of the slit diaphragm complex that connects the slit diaphragm protein nephrin to the cytoskeleton of the cell. Tyrosine phosphorylation of slit diaphragm molecules can influence their surface expression， but it is unknown whether tyrosine phosphorylation events of CD2AP are also physiologically relevant to slit diaphragm stability.
