| Products/Services Used | Details | Operation |
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| Catalog Antibody | … from transformed and control R. rhodnii diluted in TBS-T were added to triplicate wells on microtiter plates, and incubated for 2 hours at 37°C. After washing the wells in TBS-T, 2.5% BSA was added to block for 1 hour at 37°C. The primary antibody (GenScript USA), diluted to 1 … | Get A Quote |
Chagas disease is most often transmitted to humans by Trypanosoma cruzi infected triatomine bugs， and remains a significant cause of morbidity and mortality in Central and South America. Control of Chagas disease has relied mainly on vector eradication. However， development of insect resistance has prompted us to develop a paratransgenic strategy to control vectorial transmission of T. cruzi. Here， the potential role of recombinant endoglucanases as anti-trypanosomal agents for paratransgenic application is examined. The surface of T. cruzi is covered by a thick coat of mucin-like glycoproteins that have been proposed to play a role in the binding of T. cruzi to the membrane surface of the vector gut. We ... More
