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Cost-effectiveness of direct anti-viral agents for hepatitis C virus infection and a combined intervention of syringe access and medication assisted therapy for opioid use disorders in an injection drug use population.

Clin. Infect. Dis.. 2019-08; 
StevensElizabeth R,NuciforaKimberly A,HaganHolly,JordanAshly E,UyeiJennifer,KhanBilal,DombrowskiKirk,des JarlaisDon,BraithwaiteR S
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Peptide Synthesis … In brief, 8-10 weeks old female mice were immunized at base of tail and both thighs with 200 μg of mouse MOG 79-96 peptide (custom synthesized by Genscript, NJ) emulsified in Complete Freund's Adjuvant (CFA) (Sigma, MO) that had been supplemented with M. tuberculosis … Get A Quote

摘要

There are too many plausible permutations and scale-up scenarios of combination hepatitis C (HCV) interventions for exhaustive testing in experimental trials. Therefore, we used computer simulation to project the health and economic impact of alternative combination intervention scenarios for people who inject drugs (PWID), focusing on direct anti-viral agents (DAA) and medication-assisted treatment combined with syringe access programs (MAT+).

关键词

DAA,HCV,PWID,combination intervention,cost-effective