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Akt drives buffalo casein-derived novel peptide-mediated osteoblast differentiation.

J. Nutr. Biochem.. 2019; 
ReddiSrinu,KumarNaveen,VijRishika,MadaSanusi Bello,KapilaSuman,KapilaRa
Products/Services Used Details Operation
Peptide Synthesis … bicinchoninic acid assay (Pierce, Rockford, IL, USA) using bovine serum albumin, as standard, and peptide concentration of the chemically synthesized peptides was based on the dry weight of the peptides. Chemical synthesized peptides were purchased from GenScript Corp … Get A Quote

摘要

Milk is a potential nutraceutical with wide range of bioactive compounds that are antioxidative, antimicrobial, antithrombotic, immunomodulatory, opioid and antihypertensive. Various intervention studies with milk reflect its stupendous role in elevating bone mineral density. Milk and milk products have shown a preventive effect in bone loss during pre- and postmenopausal women. Since, milk is proved to have a vital role in bone health promotion, there is a need to identify bioactive compounds within it. Recently we have reported four novel peptides from milk casein for their osteoblast proliferation activity. Their role in differentiation and the signaling cascade evoked by them have not been studi... More

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