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Tetranectin gene deletion induces Parkinson's disease by enhancing neuronal apoptosis

Biochemical and Biophysical Research Communications. 2015;

Chen Z , Wang E , Hu R , Sun Y , Zhang L , Jiang J , Zhang Y , Jiang H

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Proteins, Expression, Isolation and Analysis	… Blots shown are representative of at least three independent experiments performed 26 Caspase-3 activity assay Caspase-3 activity in the lysates was detected using a colorimetric assay kit (Genscript, Piscataway, NJ, USA) according to the manufacturer's instructions …	Get A Quote

摘要

arkinson's disease (PD) is a chronic neurodegenerative disorder characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). We previously identified tetranectin (TET) as a potential biomarker for PD whose expression is downregulated in the cerebrospinal fluid of PD patients.