资源 » 参考数据库 » 客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

Human POLD1 modulates cell cycle progression and DNA damage repair.

BMC Biochem.. 2015-06;

SongJing，HongPing，LiuChengeng，ZhangYueqi，WangJinling，WangPeic

Products/Services Used	Details	Operation
Catalog Antibody	… for 1 h at room temperature The blots were then incubated with antibodies against POLD1 and GAPDH (1:2000 dilution; GenScript, USA) at 4 °C overnight After incubation with the corresponding …	Get A Quote

摘要

The activity of eukaryotic DNA polymerase delta (Pol δ) plays an essential role in genome stability through its effects on DNA replication and repair. The p125 catalytic subunit of Pol δ is encoded by POLD1 gene in human cells. To clarify biological functions of POLD1， we investigated the effects of POLD1 overexpression or downregulation on cell proliferation， cell cycle progression， DNA synthesis and oxidative DNA damage induced by H2O2.