| Products/Services Used | Details | Operation |
|---|---|---|
| Peptide Synthesis | eptide P1 Genscript N/A Peptide P2 Genscript N/A Peptide P3 cyclicc Genscript N/A Peptide P4 Genscript N/A Peptide P5 cyclicd Genscript N/A Peptide P6 Genscript N/A Peptide P7 Genscript N/A Peptide P8 Genscript N/A Peptide P9 Genscript N/A Peptide P10 Genscript N/A Peptide P11 Genscript N/A Peptide P12 Genscript N/A Peptide P13 Genscript N/A Peptide P14 Genscript N/A Peptide P15 Genscript N/A (Continued on next page) e1 Cell 172, 1–11.e1–e6, January 25, 2018 Please cite this article in press as: Tucker et al., Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries, Cell (2018), https://doi.org/10.1016/j.cell.2017.12.009 CONTACT FOR REAGENT AND RESOURCE SHARING Requests for resources and reagents should be directed and will be fulfilled by the Lead Contact, Bryan W. Davies (bwdavies@austin. utexas.edu). Continued REAGENT or RESOURCE SOURCE IDENTIFIER Peptide P16 Genscript N/A Peptide P17 Genscript N/A Peptide P18 Genscript N/A Peptide P3 Genscript N/A Peptide P5 Genscript N/A Control Peptide C1 Genscript N/A | Get A Quote |
Peptides have great potential to combat antibiotic resistance. While many platforms can screen peptides for their ability to bind to target cells， there are virtually no platforms that directly assess the functionality of peptides. This limitation is exacerbated when identifying antimicrobial peptides because the phenotype， death， selects against itself and has caused a scientific bottleneck that confines research to a few naturally occurring classes of antimicrobial peptides. We have used this seeming dissonance to develop Surface Localized Antimicrobial Display (SLAY)， a platform that allows screening of unlimited numbers of peptides of any length， composition， and structure in a single tube for a... More
