Products/Services Used | Details | Operation |
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Proteins, Expression, Isolation and Analysis | … Male Balb/c mice were purchased from Liaoning ChangSheng Biotechnology Co. LTD (Benxi, China) … IL-6, IL-10, as well as TNF-α Elisa kit were purchased from ThermoFisher Scientific (Shanghai, China). ELISA Kit for LPS was purchased from GenScript USA Inc … | Get A Quote |
In our study, the ameliorative effect of salidroside (SAL) from Rhodiola Rosea L. on the intestinal microflora subject to furan-induced liver injury in a mouse model was investigated by 16 S rDNA, oxidative indexes, LPS and cytokine levels. The results demonstrated that SAL alleviated hepatic oxidative injury by inhibiting the activities of AST, ALT and the content of MDA, and promoting the activities of SOD, GSH and GST, compared to the furan-treated group. SAL significantly modified the intestinal microbial diversity and downregulated the circulating levels of serum LPS, IL-6, and TNF-α, as well as enhanced the content of IL-10. Importantly, SAL dramatically increased LPS-suppressing ... More