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Improved campesterol production in engineered Yarrowia lipolytica strains.

Biotechnol. Lett.. 2017-07; 
ZhangYu, WangYing, YaoMingdong, LiuHong, ZhouXiao, XiaoWenhai, YuanYin
Products/Services Used Details Operation
Codon Optimization … lipolytica ATCC201249. The genes encoding heterologous DHCR7 were codon optimized (Supplementary Table 3) and synthesized by Genscript Inc. (China). They were carried by plasmid pUC57-Kan (Supplementary Table 1). All … Get A Quote

摘要

To engineer Yarrowia lipolytica for improving the heterologous production of campesterol (a key precursor to manufacture pharmaceutical steroids).

关键词

7-Dehydrocholesterol reductase,Campesterol,Metabolic engineering,Oil utilization,Synthetic biology,Yarrowia lipoly