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Identification of antigenic Sarcoptes scabiei proteins for use in a diagnostic test and of non-antigenic proteins that may be immunomodulatory

PLoS Negl Trop Dis. 2017-06;

MorganMarjorie S, RiderS Dean, ArlianLar

Products/Services Used	Details	Operation
Codon Optimization	… canis [20]. Recombinant protein expression and purification. Gene sequences for selected proteins were synthesized by GenScript (Piscataway, NJ) with the open reading frame being codon-optimized for expression in E. coli …	Get A Quote

摘要

Scabies， caused by the mite， Sarcoptes scabiei， infects millions of humans， and many wild and domestic mammals. Scabies mites burrow in the lower stratum corneum of the epidermis of the skin and are the source of substances that are antigenic or modulate aspects of the protective response of the host. Ordinary scabies is a difficult disease to diagnose.