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Renal protective effects of thymoquinone against sodium nitrite-induced chronic toxicity in rats: Impact on inflammation and apoptosis

Life Sci.. 2017-07;

ElsherbinyNehal M, MaysarahNadia M, El-SherbinyMohamed, Al-GayyarMoham

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Proteins, Expression, Isolation and Analysis	… Estimation of activity of caspase-8, caspase 9 and caspase-3 in renal tissues. The enzyme activity of caspase-8, caspase-9 and caspase-3in renal tissue was assessed by colorimetric method using kits from GenScript (Piscataway, NJ, USA) following manufacturer's protocol. 2.6 …	Get A Quote

摘要

Sodium nitrite is a widely used color fixative and preservative. However， it has been reported to exert deleterious toxic effects on various body organs. Moreover， thymoquinone (TQ)， the active constituent of Nigella sativa oil is known to possess beneficial antioxidant and anti-inflammatory effects. The present study was conducted to evaluate the potential protective effects of TQ against sodium nitrite-induced renal toxicity.