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Phage Abp1 Rescues Human Cells and Mice from Infection by Pan-Drug Resistant Acinetobacter Baumannii

Cell. Physiol. Biochem.. 2017-01;

YinSupeng, HuangGuangtao, ZhangYulong, JiangBei, YangZichen, DongZhiwei, YouBo, YuanZhiqiang, HuFuquan, ZhaoYan, PengY

Products/Services Used	Details	Operation
Proteins, Expression, Isolation and Analysis	… The characteristics of this phage are described in our previous report [11]. Endotoxin was removed from Abp1 cultures using the ToxinEraser endotoxin removal kit (GenScript, China). Bacteriophage resistance assay. Serial …	Get A Quote

摘要

As an "ESKAPE" pathogen， Acinetobacter baumannii is one of the leading causes of drug-resistant infections in humans. Phage therapy may be a useful strategy in treating infections caused by drug-resistant A. baumannii. Among 21 phage strains that were isolated and described earlier， we investigated the therapeutic efficacy of Abp1 because of its relatively wide host range.