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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 67/4751 每页显示数量

Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies

Authors: J Sebastian Temme, Jennifer A Crainic, Laura M Walker, Weizhun Yang, Zibin Tan, Xuefei Huang, Jeffrey C Gildersleeve

Journal: J Biol Chem

PubMed ID: 36087840

Doi: 10.1016/j.jbc.2022.102468

Products & Services: Plasmid DNA Preparation

Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor

Authors: Xiyuan Zhang, Hannah E Lou, Vishaka Gopalan, Zhihui Liu, Hilda M Jafarah, Haiyan Lei, Paige Jones, Carly M Sayers, Marielle E Yohe, Prashant Chittiboina, Brigitte C Widemann, Carol J Thiele, Michael C Kelly, Sridhar Hannenhalli, Jack F Shern

Journal: Cell Rep

PubMed ID: 36130486

Doi: 10.1016/j.celrep.2022.111363

Products & Services: Custom Vector Construction

Alamandine alleviated heart failure and fibrosis in myocardial infarction mice

Authors: Kun Zhao, Tianhua Xu, Yukang Mao, Xiaoguang Wu, Dongxu Hua, Yanhui Sheng, Peng Li

Journal: Biol Direct

PubMed ID: 36167556

Doi: 10.1186/s13062-022-00338-6

Products & Services: Custom DNA/RNA Oligos

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

Authors: Jordan R Willis, Zachary T Berndsen, Krystal M Ma, Jon M Steichen, Torben Schiffner, Elise Landais, Alessia Liguori, Oleksandr Kalyuzhniy, Joel D Allen, Sabyasachi Baboo, Oluwarotimi Omorodion, Jolene K Diedrich, Xiaozhen Hu, Erik Georgeson, Nicole Phelps, Saman Eskandarzadeh, Bettina Groschel, Michael Kubitz, Yumiko Adachi, Tina-Marie Mullin, Nushin B Alavi, Samantha Falcone, Sunny Himansu, Andrea Carfi, Ian A Wilson, John R Yates, James C Paulson, Max Crispin, Andrew B Ward, William R Schief

Journal: Immunity

PubMed ID: 36179689

Doi: 10.1016/j.immuni.2022.09.001

Products & Services: Recombinant Antibody Expression

Intranasal Immunization with Liposome-Displayed Receptor-Binding Domain Induces Mucosal Immunity and Protection against SARS-CoV-2

Authors: Wei-Chiao Huang, Kevin Chiem, Luis Martinez-Sobrido, Jonathan F Lovell

Journal: Pathogens

PubMed ID: 36145467

Doi: 10.3390/pathogens11091035

Products & Services: Catalog Antibody

Inactivated COVID-19 vaccines: durability of Covaxin/BBV152 induced immunity against variants of concern

Authors: Nathella Pavan Kumar, V V Banurekha, C P Girish Kumar, Arul Nancy, Chandrasekaran Padmapriyadarsini, Sakila Shankar, Luke Elizabeth Hanna, Manoj Murhekar, K R Uma Devi, Subash Babu

Journal: J Travel Med

PubMed ID: 35900009

Doi: 10.1093/jtm/taac088

Products & Services: Recombinant Proteins

High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity

Authors: Rodrigo Vazquez-Lombardi, Johanna S Jung, Fabrice S Schlatter, Anna Mei, Natalia Rodrigues Mantuano, Florian Bieberich, Kai-Lin Hong, Jakub Kucharczyk, Edo Kapetanovic, Erik Aznauryan, Cédric R Weber, Alfred Zippelius, Heinz Läubli, Sai T Reddy

Journal: Immunity

PubMed ID: 36174557

Doi: 10.1016/j.immuni.2022.09.004

Products & Services: Peptide Synthesis

mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts

Authors: Denzil Furtado, Christina Cortez-Jugo, Ya Hui Hung, Ashley I Bush, Frank Caruso

Journal: Mol Pharm

PubMed ID: 36125338

Doi: 10.1021/acs.molpharmaceut.2c00463

Products & Services: GenParts™ DNA Fragments

A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity

Authors: Lian-Sheng Cheng, Yong-Feng Cheng, Wen-Ting Liu, Aolin Shen, Dayan Zhang, Tingjuan Xu, Wu Yin, Min Cheng, Xiaopeng Ma, Fengrong Wang, Qun Zhao, Xiaoli Zeng, Yan Zhang, Guodong Shen

Journal: J Transl Med

PubMed ID: 36076251

Doi: 10.1186/s12967-022-03619-w

Products & Services: Mammalian Expression

H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity

Authors: Huasong Ai , Maoshen Sun , Aijun Liu , Zixian Sun , Tingting Liu , Lin Cao , Lujun Liang , Qian Qu , Zichen Li , Zhiheng Deng , Zebin Tong , Guochao Chu , Xiaolin Tian , Haiteng Deng , Suwen Zhao , Jia-Bin Li , Zhiyong Lou , Lei Liu

Journal: Nat Chem Biol

PubMed ID: 35739357

Doi: 10.1038/s41589-022-01067-7

Products & Services: Gene Synthesis

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