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Structural basis of TRPV3 inhibition by an antagonist
Authors: Junping Fan, Linghan Hu, Zongwei Yue, Daohong Liao, Fusheng Guo, Han Ke, Daohua Jiang, Yong Yang, Xiaoguang Lei
Journal: Nat Chem Biol
PubMed ID: 36302896
Doi: 10.1038/s41589-022-01166-5
Products & Services: Catalog Peptides   
Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition
Authors: Yasmin Natalia Serina Secanechia, Isabelle Bergiers, Matt Rogon, Christian Arnold, Nicolas Descostes, Stephanie Le, Natalia López-Anguita, Kerstin Ganter, Chrysi Kapsali, Lea Bouilleau, Aaron Gut, Auguste Uzuotaite, Ayshan Aliyeva, Judith B Zaugg, Christophe Lancrin
Journal: Sci Rep
PubMed ID: 36217016
Doi: 10.1038/s41598-022-20906-0
Products & Services: Gene Synthesis   
Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates
Authors: Lochana M Seenappa, Aniela Jakubowski, Martin P Steinbuck, Erica Palmer, Christopher M Haqq, Crystal Carter, Jane Fontenot, Francois Villinger, Lisa K McNeil, Peter C DeMuth
Journal: npj Vaccines
PubMed ID: 36307453
Doi: 10.1038/s41541-022-00560-3
Products & Services: Catalog Peptides   
Development of Enzymatic Depletion Methods for Preparation of Small Extracellular Vesicles with Long Blood-Circulation Half-Life
Authors: Yuki Kobayashi, Shimpei Kitamura, Yuki Takahashi, Yoshinobu Takakura
Journal: Pharm Res
PubMed ID: 36195822
Doi: 10.1007/s11095-022-03405-9
Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP
Authors: Maria A Schumacher, Mirka E Wörmann, Max Henderson, Raul Salinas, Andreas Latoscha, Mahmoud M Al-Bassam, Kumar Siddharth Singh, Elaine Barclay, Katrin Gunka, Natalia Tschowri
Journal: Nat Commun
PubMed ID: 36192422
Doi: 10.1038/s41467-022-33537-w
Products & Services: PCR Cloning and Subcloning   
TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model
Authors: Nunziata Maio, Sara Cherry, David C Schultz, Brett L Hurst, W Marston Linehan, Tracey A Rouault
Journal: iScience
PubMed ID: 36093377
Doi: 10.1016/j.isci.2022.105074
Products & Services: Immunoassay Development Services   
Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans
Authors: Marcele P Martins, Mariana A B Morais, Gabriela F Persinoti, Rafael H Galinari, Li Yu, Yoshihisa Yoshimi, Fernanda B Passos Nunes, Tatiani B Lima, Shayla F Barbieri, Joana L M Silveira, Vincent Lombard, Nicolas Terrapon, Paul Dupree, Bernard Henrissat, Mário T Murakami
Journal: Acta Crystallogr D Struct Biol
PubMed ID: 36322419
Doi: 10.1107/S2059798322009561
Products & Services: Custom Vector Construction   
MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases
Authors: Zahra Mohtashami, Mithalesh K Singh, Nasim Salimiaghdam, Mustafa Ozgul, M Cristina Kenney
Journal: Int J Mol Sci
PubMed ID: 36233287
Doi: 10.3390/ijms231911991
Products & Services: Gene Synthesis   
Velcrin-induced selective cleavage of tRNA(TAA) by SLFN12 causes cancer cell death
Authors: Sooncheol Lee, Stephanie Hoyt, Xiaoyun Wu, Colin Garvie, Joseph McGaunn, Mrinal Shekhar, Marcus Tötzl, Matthew G Rees, Andrew D Cherniack, Matthew Meyerson, Heidi Greulich
Journal: Nat Chem Biol
PubMed ID: 36302897
Doi: 10.1038/s41589-022-01170-9
Products & Services: Gene Synthesis   
CD4-1 and CD8α T lymphocytes subsets in spotted sea bass (Lateolabrax maculatus) and comparison on antigenicity of T lymphocytes subsets in other three marine fish species
Authors: Xiaoyu Jiang, Jing Xing, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan
Journal: Fish Shellfish Immunol
PubMed ID: 36210001
Doi: 10.1016/j.fsi.2022.10.004
Products & Services: Catalog Antibody   
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