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Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
Authors: Nikolas Friedrich, Emanuel Stiegeler, Matthias Glögl, Thomas Lemmin, Simon Hansen, Claus Kadelka, Yufan Wu, Patrick Ernst, Liridona Maliqi, Caio Foulkes, Mylène Morin, Mustafa Eroglu, Thomas Liechti, Branislav Ivan, Thomas Reinberg, Jonas V Schaefer, Umut Karakus, Stephan Ursprung, Axel Mann, Peter Rusert, Roger D Kouyos, John A Robinson, Huldrych F Günthard, Andreas Plückthun, Alexandra Trkola
Journal: Nat Commun
PubMed ID: 34795280
Doi: 10.1038/s41467-021-27075-0
Products & Services: GenParts™ DNA Fragments   
Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation
Authors: Hengjun Cui, Andreas U Müller, Marc Leibundgut, Jiawen Tian, Nenad Ban, Eilika Weber-Ban
Journal: Nat Commun
PubMed ID: 34789727
Doi: 10.1038/s41467-021-26848-x
Products & Services: GenParts™ DNA Fragments   
Tryptophan Side-Chain Oxidase Enzyme Suppresses Hepatocellular Carcinoma Growth through Degradation of Tryptophan
Authors: Yang Ai, Ben Wang, Shuai Xiao, Sang Luo, Yefu Wang
Journal: Int J Mol Sci
PubMed ID: 34830310
Doi: 10.3390/ijms222212428
Products & Services: Endotoxin Detection & Removal System   
Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination
Authors: Wooseob Kim, Julian Q Zhou, Alexandria J Sturtz, Stephen C Horvath, Aaron J Schmitz, Tingting Lei, Elizaveta Kalaidina, Mahima Thapa, Wafaa B Alsoussi, Alem Haile, Michael K Klebert, Teresa Suessen, Luis Parra-Rodriguez, Philip A Mudd, William D Middleton, Sharlene A Teefey, Iskra Pusic, Jane A O'Halloran, Rachel M Presti, Jackson S Turner, Ali H Ellebedy
Journal: biorxiv
PubMed ID: 34751268
Doi: 10.1101/2021.10.31.466651
Products & Services: Custom Vector Construction   
MiR-702-3p inhibits the inflammatory injury in septic H9c2 cells by regulating NOD1
Authors: Chun Liu, Yang Yang, Guiwen Liang, Aixian Zhang, Feng Xu
Journal: Transpl Immunol
PubMed ID: 34774740
Doi: 10.1016/j.trim.2021.101493
Products & Services: Custom Vector Construction   
T cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas
Authors: Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O Breckwoldt, Gerald Willimksy, Stefan B Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, Lukas Bunse
Journal: Clin Cancer Res
PubMed ID: 34782365
Doi: 10.1158/1078-0432.CCR-21-1881
Products & Services: Custom DNA/RNA Oligos   
Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus
Authors: Ebru Destan, Busra Yuksel, Bradley B Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A Francis, Hasan DeMirci
Journal: Sci Rep
PubMed ID: 34819551
Doi: 10.1038/s41598-021-02180-8
Products & Services: Codon Optimization   
Proteolytic processing of plant proteins by potyvirus NIa proteases
Authors: Huogen Xiao, Etienne Lord, Hélène Sanfaçon
Journal: J Virol
PubMed ID: 34757836
Doi: 10.1128/JVI.01444-21
Products & Services: Codon Optimization   
Structure of native HIV-1 cores and their interactions with IP6 and CypA
Authors: Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till Böcking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang
Journal: Sci Adv
PubMed ID: 34797722
Doi: 10.1126/sciadv.abj5715
Products & Services: Codon Optimization   
Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity
Authors: Jonathan P Renn, Justin Y A Doritchamou, Bergeline C Nguemwo Tentokam, Robert D Morrison, Matthew V Cowles, Martin Burkhardt, Rui Ma, Niraj H Tolia, Michal Fried, Patrick E Duffy
Journal: Commun Biol
PubMed ID: 34799664
Doi: 10.1038/s42003-021-02787-7
Products & Services: Codon Optimization   
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