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页码: 201/4751 每页显示数量
β-arrestin2 mediates the hippocampal dopaminergic system in autistic mouse through the ERK signaling pathway
Authors: Yu Zhou, Yamei Liu, Qingyu Peng, Feng Li, Fuxue Chen
Journal: Behav Brain Res
PubMed ID: 35398487
Doi: 10.1016/j.bbr.2022.113888
CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA
Authors: Beverly Y Mok, Anna V Kotrys, Aditya Raguram, Tony P Huang, Vamsi K Mootha, David R Liu
Journal: Nat Biotechnol
PubMed ID: 35379961
Doi: 10.1038/s41587-022-01256-8
Products & Services: Mammalian Expression   
Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells
Authors: Kareem A Heslop, Pieter Burger, Christiana Kappler, Ashish K Solanki, Monika Gooz, Yuri K Peterson, Catherine Mills, Thomas Benton, Stephen A Duncan, Patrick M Woster, Eduardo N Maldonado
Journal: Biomed Pharmacother
PubMed ID: 35447542
Doi: 10.1016/j.biopha.2022.112928
Products & Services: Plasmid DNA Preparation   
Ultrasensitive CRISPR/Cas12a-Driven SERS Biosensor for On-Site Nucleic Acid Detection and Its Application to Milk Authenticity Testing
Authors: Ruiyuan Pan, Jianghua Liu, Panxue Wang, Di Wu, Jian Chen, Yongning Wu, Guoliang Li
Journal: J Agric Food Chem
PubMed ID: 35380812
Doi: 10.1021/acs.jafc.1c08262
Products & Services: Custom DNA/RNA Oligos   
The development of a candidate of desensitization vaccines against Der f 2 nearly without IgE-binding activity
Authors: Xiao-Jing Ling, Chen Pan, Ling-Xiao Tan, Ying Zhu, Yu-Xing Yang, Xiao-Fei Zeng, Jin-Lyu Sun, Ji-Fu Wei, Chen Lu
Journal: Immunobiology
PubMed ID: 35580444
Doi: 10.1016/j.imbio.2022.152217
A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells
Authors: Yumei Li, Lingjun Wu, Yueying Liu, Siwen Ma, Biyi Huang, Xianjing Feng, Hui Wang
Journal: Transl Oncol
PubMed ID: 35477065
Doi: 10.1016/j.tranon.2022.101424
Products & Services: Mammalian Expression   
The Model for Mucolipidosis Type IV
Authors: Claire Y Allan, Paul R Fisher
Journal: Front Cell Dev Biol
PubMed ID: 35493081
Doi: 10.3389/fcell.2022.741967
Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action
Authors: Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A Zubarev, Stig Linder, Pádraig D'Arcy
Journal: Front Oncol
PubMed ID: 35530310
Doi: 10.3389/fonc.2022.852980
Products & Services: Oligo pool   
Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota
Authors: Matthew P Ostrowski, Sabina Leanti La Rosa, Benoit J Kunath, Andrew Robertson, Gabriel Pereira, Live H Hagen, Neha J Varghese, Ling Qiu, Tianming Yao, Gabrielle Flint, James Li, Sean P McDonald, Duna Buttner, Nicholas A Pudlo, Matthew K Schnizlein, Vincent B Young, Harry Brumer, Thomas M Schmidt, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Bruce Hamaker, Emiley A Eloe-Fadrosh, Ashootosh Tripathi, Phillip B Pope, Eric C Martens
Journal: Nat Microbiol
PubMed ID: 35365790
Doi: 10.1038/s41564-022-01093-0
Products & Services: GenParts™ DNA Fragments   
G-protein biased signaling agonists of Dopamine D3 receptor promote distinct activation patterns of ERK1/2
Authors: Wei Xu, Frank Bearoff, Sandhya Kortagere
Journal: Pharmacol Res
PubMed ID: 35429668
Doi: 10.1016/j.phrs.2022.106223
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