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Specific knockdown of by CRISPR-CasRx prevents acquired sensorineural hearing loss in mice
Authors: Yang Guo, Lei Han, Shuang Han, Honghai Tang, Shengyi Wang, Chong Cui, Bing Chen, Huawei Li, Yilai Shu
Journal: Mol Ther Nucleic Acids
PubMed ID: 35615000
Doi: 10.1016/j.omtn.2022.04.014
Immmunoinformatics-based design of a multi-epitope vaccine with CTLA-4 extracellular domain to combat Helicobacter pylori
Authors: Zhenyu Ru, Mingkai Yu, Yuejie Zhu, Zhiqiang Chen, Fengbo Zhang, Zhiqiang Zhang, Jianbing Ding
Journal: FASEB J
PubMed ID: 35294065
Doi: 10.1096/fj.202101538RR
Products & Services: Molecular Biology Tools   
p53 alters intracellular Ca signaling through regulation of TRPM4
Authors: Sven Kappel, Daniela Ross-Kaschitza, Barbara Hauert, Karen Rother, Christine Peinelt
Journal: Cell Calcium
PubMed ID: 35500522
Doi: 10.1016/j.ceca.2022.102591
a New IFN-Inducible Human Member of the Ly6a Subfamily Expressed by Spleen Cells and Associated with Inflammation and Viral Resistance
Authors: Moriya Shmerling, Michael Chalik, Nechama I Smorodinsky, Alan Meeker, Sujayita Roy, Orit Sagi-Assif, Tsipi Meshel, Artem Danilevsky, Noam Shomron, Shmuel Levinger, Bar Nishry, David Baruchi, Avital Shargorodsky, Ravit Ziv, Avital Sarusi-Portuguez, Maoz Lahav, Marcelo Ehrlich, Bryony Braschi, Elspeth Bruford, Isaac P Witz, Daniel H Wreschner
Journal: Immunohorizons
PubMed ID: 35440514
Doi: 10.4049/immunohorizons.2200018
Products & Services: DNA Sequencing   
Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation
Authors: Koen K A Van Rompay, Katherine J Olstad, Rebecca L Sammak, Joseph Dutra, Jennifer K Watanabe, Jodie L Usachenko, Ramya Immareddy, Jamin W Roh, Anil Verma, Yashavanth Shaan Lakshmanappa, Brian A Schmidt, Clara Di Germanio, Nabeela Rizvi, Hongwei Liu, Zhong-Min Ma, Mars Stone, Graham Simmons, Larry J Dumont, A Mark Allen, Sarah Lockwood, Rachel E Pollard, Rafael Ramiro de Assis, JoAnn L Yee, Peter B Nham, Amir Ardeshir, Jesse D Deere, Aarti Jain, Philip L Felgner, Lark L Coffey, Smita S Iyer, Dennis J Hartigan-O'Connor, Michael P Busch, J Rachel Reader
Journal: PLoS Pathog
PubMed ID: 35443018
Doi: 10.1371/journal.ppat.1009925
Products & Services: Recombinant Antibody Expression   
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice
Authors: Liqin Liu, Tingting Chen, Lizhi Zhou, Jie Sun, Yuqian Li, Meifeng Nie, Hualong Xiong, Yuhe Zhu, Wenhui Xue, Yangtao Wu, Tingting Li, Tianying Zhang, Zhibo Kong, Hai Yu, Jun Zhang, Ying Gu, Qingbing Zheng, Qinjian Zhao, Ningshao Xia, Shaowei Li
Journal: Front Microbiol
PubMed ID: 35558112
Doi: 10.3389/fmicb.2022.854630
Products & Services: Catalog Peptides   
Formulation of simvastatin within high density lipoprotein enables potent tumour radiosensitisation
Authors: Pouya Dehghankelishadi, Michelle F Maritz, Nicole Dmochowska, Parisa Badiee, Edward Cheah, Ivan Kempson, Ross I Berbeco, Benjamin Thierry
Journal: J Control Release
PubMed ID: 35447296
Doi: 10.1016/j.jconrel.2022.04.017
Products & Services: Peptide Synthesis   
Cathepsin B-Cleavable Polymeric Photosensitizer Prodrug for Selective Photodynamic Therapy: In Vitro Studies
Authors: Manish Jain, Jordan Bouilloux, Ines Borrego, Stéphane Cook, Hubert van den Bergh, Norbert Lange, Georges Wagnieres, Marie-Noelle Giraud
Journal: Pharmaceuticals (Basel)
PubMed ID: 35631388
Doi: 10.3390/ph15050564
Products & Services: Biochemicals   
Tuning the Sensitivity of Genetically Encoded Fluorescent Potassium Indicators through Structure-Guided and Genome Mining Strategies
Authors: Cristina C Torres Cabán, Minghan Yang, Cuixin Lai, Lina Yang, Fedor V Subach, Brian O Smith, Kiryl D Piatkevich, Edward S Boyden
Journal: ACS Sens
PubMed ID: 35427452
Doi: 10.1021/acssensors.1c02201
Products & Services: Custom Vector Construction   
Role of sirtuin 1 in the brain development in congenital hypothyroidism rats via the regulation of p53 signaling pathway
Authors: Xiaofang Wei, Juan Tan, Hui Gao
Journal: Bioengineered
PubMed ID: 35383535
Doi: 10.1080/21655979.2022.2060626
Products & Services: Custom DNA/RNA Oligos   
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