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Enhanced immunogenicity of a positively supercharged archaeon thioredoxin scaffold as a cell-penetrating antigen carrier for peptide vaccines
Authors: Davide Cavazzini, Gloria Spagnoli, Filipe Colaco Mariz, Filippo Reggiani, Stefano Maggi, Valentina Franceschi, Gaetano Donofrio, Martin Müller, Angelo Bolchi, Simone Ottonello
Journal: Front Immunol
PubMed ID: 36032169
Doi: 10.3389/fimmu.2022.958123
Products & Services: Catalog Peptides   
Disruption of nuclear envelope integrity as a possible initiating event in tauopathies
Authors: Marine Prissette, Wen Fury, Matthew Koss, Claudia Racioppi, Daria Fedorova, Ella Dragileva, Georgia Clarke, Taylor Pohl, John Dugan, Diana Ahrens, Joyce Chiu, Charleen Hunt, Chia-Jen Siao, Tara Young, Arijit Bhowmick, Vitaliy Rogulin, Mathieu Desclaux, Eric Y Hayden, Michael Podgorski, Min Gao, Lynn E Macdonald, David Frendewey, George D Yancopoulos, Brian Zambrowicz
Journal: Cell Rep
PubMed ID: 36001963
Doi: 10.1016/j.celrep.2022.111249
Products & Services: Synthetic sgRNA and crRNA Service   
Low pH structure of heliorhodopsin reveals chloride binding site and intramolecular signaling pathway
Authors: Jessica E Besaw, Jörg Reichenwallner, Paolo De Guzman, Andrejs Tucs, Anling Kuo, Takefumi Morizumi, Koji Tsuda, Adnan Sljoka, R J Dwayne Miller, Oliver P Ernst
Journal: Sci Rep
PubMed ID: 35977989
Doi: 10.1038/s41598-022-17716-9
Products & Services: Custom Vector Construction   
Identification and characterization of a novel peptide from rainbow trout (Oncorhynchus mykiss) with antimicrobial activity against Streptococcus iniae
Authors: Joseph F A Varga, Sascha R Brunner, Grant Cheng, Daniel Min, Marc G Aucoin, Andrew C Doxey, Brian Dixon
Journal: Dev Comp Immunol
PubMed ID: 36044968
Doi: 10.1016/j.dci.2022.104518
Products & Services: Catalog Peptides   
A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane
Authors: Andrés Guillén-Samander, Yumei Wu, S Sebastian Pineda, Francisco J García, Julia N Eisen, Marianna Leonzino, Berrak Ugur, Manolis Kellis, Myriam Heiman, Pietro De Camilli
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35994651
Doi: 10.1073/pnas.2205425119
Products & Services: Gene Synthesis   
Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Ad26CoV2S Vaccination in People Living With Human Immunodeficiency Virus (HIV)
Authors: Khadija Khan, Gila Lustig, Mallory Bernstein, Derseree Archary, Sandile Cele, Farina Karim, Muneerah Smith, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Yoliswa Miya, Ntombifuthi Mthabela, Nombulelo P Magula, Richard Lessells, Tulio de Oliveira, Bernadett I Gosnell, Salim Abdool Karim, Nigel Garrett, Willem Hanekom, Linda-Gail Bekker, Glenda Gray, Jonathan M Blackburn, Mahomed-Yunus S Moosa, Alex Sigal
Journal: Clin Infect Dis
PubMed ID: 34893824
Doi: 10.1093/cid/ciab1008
Products & Services: Monoclonal Antibody Services   
Comparison of antibody response durability of mRNA-1273, BNT162b2, and Ad26COV2S SARS-CoV-2 vaccines in healthcare workers
Authors: Wendy M Brunner, Daniel Freilich, Jennifer Victory, Nicole Krupa, Melissa B Scribani, Paul Jenkins, Emily G Lasher, Amanda Fink, Anshini Shah, Peggy Cross, Valerie Bush, Laura J Peek, Gary A Pestano, Anne M Gadomski
Journal: Int J Infect Dis
PubMed ID: 36044963
Doi: 10.1016/j.ijid.2022.08.022
Regulation of Host Immune Response against Proteins via Computational mRNA Vaccine Design through Transcriptional Modification
Authors: Muhammad Naveed, Khizra Jabeen, Rubina Naz, Muhammad Saad Mughal, Ali A Rabaan, Muhammed A Bakhrebah, Fahad M Alhoshani, Mohammed Aljeldah, Basim R Al Shammari, Mohammed Alissa, Amal A Sabour, Rana A Alaeq, Maha A Alshiekheid, Mohammed Garout, Mohammed S Almogbel, Muhammad A Halwani, Safaa A Turkistani, Naveed Ahmed
Journal: Microorganisms
PubMed ID: 36014038
Doi: 10.3390/microorganisms10081621
Products & Services: Molecular Biology Tools   
Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity
Authors: Yvonne Joho, Vanessa Vongsouthi, Matthew A Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A Kaczmarski, Alessandro T Caputo, Santana Royan, Colin J Jackson, Albert Ardevol
Journal: Biochemistry
PubMed ID: 35951410
Doi: 10.1021/acs.biochem.2c00323
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results
Authors: Christine D Palmer, Amy R Rappaport, Matthew J Davis, Meghan G Hart, Ciaran D Scallan, Sue-Jean Hong, Leonid Gitlin, Lauren D Kraemer, Sonia Kounlavouth, Aaron Yang, Lindsey Smith, Desiree Schenk, Mojca Skoberne, Kiara Taquechel, Martina Marrali, Jason R Jaroslavsky, Charmaine N Nganje, Elizabeth Maloney, Rita Zhou, Daniel Navarro-Gomez, Adrienne C Greene, Gijsbert Grotenbreg, Renee Greer, Wade Blair, Minh Duc Cao, Shawn Chan, Kyounghwa Bae, Alexander I Spira, Sameek Roychowdhury, David P Carbone, Brian S Henick, Charles G Drake, Benjamin J Solomon, Daniel H Ahn, Amit Mahipal, Steve B Maron, Benny Johnson, Raphael Rousseau, Roman Yelensky, Chih-Yi Liao, Daniel V T Catenacci, Andrew Allen, Andrew R Ferguson, Karin Jooss
Journal: Nat Med
PubMed ID: 35970920
Doi: 10.1038/s41591-022-01937-6
Products & Services: Plasmid DNA Preparation   
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