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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 99/4749 每页显示数量

Case report: A novel loss-of-function pathogenic variant in the KCNA1 cytoplasmic N-terminus causing carbamazepine-responsive type 1 episodic ataxia

Authors: Rían W Manville, Richard Sidlow, Geoffrey W Abbott

Journal: Front Neurol

PubMed ID: 36016548

Doi: 10.3389/fneur.2022.975849

Products & Services: Custom Vector Construction

LIMP2 gene, evolutionarily conserved regulation by TFE3, relieves lysosomal stress induced by cholesterol

Authors: Hanze Guo, Yingying Zhu, Jiarui Li, Qipeng Zhang, Yan Chi

Journal: Life Sci

PubMed ID: 35987341

Doi: 10.1016/j.lfs.2022.120888

Products & Services: Custom Vector Construction

Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase

Authors: Samantha N Muellers, Mattias M Nyitray, Nicholas Reynarowych, Edina Saljanin, Annie Laurie Benzie, Alan R Schoenfeld, Brian J Stockman, Karen N Allen

Journal: Biochemistry

PubMed ID: 35994320

Doi: 10.1021/acs.biochem.2c00361

Products & Services: Recombinant Proteins

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

Authors: Jeroen M J Tas, Ja-Hyun Koo, Ying-Cing Lin, Zhenfei Xie, Jon M Steichen, Abigail M Jackson, Blake M Hauser, Xuesong Wang, Christopher A Cottrell, Jonathan L Torres, John E Warner, Kathrin H Kirsch, Stephanie R Weldon, Bettina Groschel, Bartek Nogal, Gabriel Ozorowski, Sandhya Bangaru, Nicole Phelps, Yumiko Adachi, Saman Eskandarzadeh, Michael Kubitz, Dennis R Burton, Daniel Lingwood, Aaron G Schmidt, Usha Nair, Andrew B Ward, William R Schief, Facundo D Batista

Journal: Immunity

PubMed ID: 35987201

Doi: 10.1016/j.immuni.2022.07.020

Products & Services: Catalog Antibody

Comparison of antibody response durability of mRNA-1273, BNT162b2, and Ad26COV2S SARS-CoV-2 vaccines in healthcare workers

Authors: Wendy M Brunner, Daniel Freilich, Jennifer Victory, Nicole Krupa, Melissa B Scribani, Paul Jenkins, Emily G Lasher, Amanda Fink, Anshini Shah, Peggy Cross, Valerie Bush, Laura J Peek, Gary A Pestano, Anne M Gadomski

Journal: Int J Infect Dis

PubMed ID: 36044963

Doi: 10.1016/j.ijid.2022.08.022

Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6

Authors: Jacob Bassett, Jenna K Rimel, Shrabani Basu, Pratik Basnet, Jie Luo, Krysta L Engel, Michael Nagel, Alexander Woyciehowsky, Christopher C Ebmeier, Craig D Kaplan, Dylan J Taatjes, Jeffrey A Ranish

Journal: J Biol Chem

PubMed ID: 36041630

Doi: 10.1016/j.jbc.2022.102433

Products & Services: Mutant Libraries

Enhanced immunogenicity of a positively supercharged archaeon thioredoxin scaffold as a cell-penetrating antigen carrier for peptide vaccines

Authors: Davide Cavazzini, Gloria Spagnoli, Filipe Colaco Mariz, Filippo Reggiani, Stefano Maggi, Valentina Franceschi, Gaetano Donofrio, Martin Müller, Angelo Bolchi, Simone Ottonello

Journal: Front Immunol

PubMed ID: 36032169

Doi: 10.3389/fimmu.2022.958123

Products & Services: Catalog Peptides

Low pH structure of heliorhodopsin reveals chloride binding site and intramolecular signaling pathway

Authors: Jessica E Besaw, Jörg Reichenwallner, Paolo De Guzman, Andrejs Tucs, Anling Kuo, Takefumi Morizumi, Koji Tsuda, Adnan Sljoka, R J Dwayne Miller, Oliver P Ernst

Journal: Sci Rep

PubMed ID: 35977989

Doi: 10.1038/s41598-022-17716-9

Products & Services: Custom Vector Construction

Mechanistic insights into global suppressors of protein folding defects

Authors: Gopinath Chattopadhyay, Jayantika Bhowmick, Kavyashree Manjunath, Shahbaz Ahmed, Parveen Goyal, Raghavan Varadarajan

Journal: PLoS Genet

PubMed ID: 36037221

Doi: 10.1371/journal.pgen.1010334

Products & Services: Proteins, Expression, Isolation and Analysis

Refolding and characterization of a diabody against Pfs25, a vaccine candidate of Plasmodium falciparum

Authors: Deepak K Jagannath, Ashwathi Valiyaparambil, Vysakh K Viswanath, Manjunath A Hurakadli, Neelagandan Kamariah, Alifia C Jafer, Chhaya Patole, Sabyasachi Pradhan, Naveen Kumar, Anirudha Lakshminarasimhan

Journal: Anal Biochem

PubMed ID: 35944694

Doi: 10.1016/j.ab.2022.114830

Products & Services: PCR Cloning and Subcloning

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