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SPTLC1 variants associated with ALS produce distinct sphingolipid signatures through impaired interaction with ORMDL proteins
Authors: Museer A Lone, Mari J Aaltonen, Aliza Zidell, Helio F Pedro, Jonas A Morales Saute, Shalett Mathew, Payam Mohassel, Carsten G Bönnemann, Eric A Shoubridge, Thorsten Hornemann
Journal: J Clin Invest
PubMed ID: 35900868
Doi: 10.1172/JCI161908
Chemoenzymatic Synthesis of SARS-CoV-2 Homogeneous O-Linked Glycopeptides for Exploring Their Inhibition Functions
Authors: Yongheng Rong, Xingyun Wang, Weian Mao, Fang Yuan, Min Chen, Shengjun Wang, Peng George Wang, Zhigang Wu, Yunjiao He, Yun Kong
Journal: ACS Infect Dis
PubMed ID: 36095241
Doi: 10.1021/acsinfecdis.2c00383
Products & Services: Monoclonal Antibody Services   
Herpes Simplex Virus 1 Glycoproteins Differentially Regulate the Activity of Costimulatory Molecules and T Cells
Authors: Harry H Matundan, Ujjaldeep Jaggi, Homayon Ghiasi
Journal: mSphere
PubMed ID: 36094100
Doi: 10.1128/msphere.00382-22
Products & Services: Recombinant Proteins   
A 1-aminocyclopropane-1-carboxylic-acid (ACC) dipeptide elicits ethylene responses through ACC-oxidase mediated substrate promiscuity
Authors: John Vaughan-Hirsch, Dongdong Li, Albert Roig Martinez, Stijn Roden, Jolien Pattyn, Shu Taira, Hitomi Shikano, Yoko Miyama, Yukari Okano, Arnout Voet, Bram Van de Poel
Journal: Front Plant Sci
PubMed ID: 36172554
Doi: 10.3389/fpls.2022.995073
Peptide-Based HDL as an Effective Delivery System for Lipophilic Drugs to Restrain Atherosclerosis Development
Authors: Junwei Gao, Ziyun Li, Jing Li, Ping Song, Jinsheng Yang, Wei Xiao, Ning Li, Ruodan Xu
Journal: Int J Nanomedicine
PubMed ID: 36097444
Doi: 10.2147/IJN.S374736
Products & Services: Gene Synthesis   
Small secreted peptides encoded on the wheat ( L) genome and their potential roles in stress responses
Authors: Dongdong Tian, Qi Xie, Zhichao Deng, Jin Xue, Wei Li, Zenglin Zhang, Yifei Dai, Bo Zheng, Tiegang Lu, Ive De Smet, Yongfeng Guo
Journal: Front Plant Sci
PubMed ID: 36212358
Doi: 10.3389/fpls.2022.1000297
Products & Services: Peptide Synthesis   
Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes
Authors: Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola, Björn Schulte, Kristin G Monaghan, Amber Begtrup, Annalaura Torella, Michele Pinelli, Anne Sophie Denommé-Pichon, Antonio Vitobello, Caroline Racine, Maria Margherita Mancardi, Courtney Kiss, Andrea Guerin, Wendy Wu, Elisabeth Gabau Vila, Bryan C Mak, Julian A Martinez-Agosto, Michael B Gorin, Bugrahan Duz, Yavuz Bayram, Claudia M B Carvalho, Jaime E Vengoechea, David Chitayat, Tiong Yang Tan, Bert Callewaert, Bernd Kruse, Lynne M Bird, Laurence Faivre, Marcella Zollino, Saskia Biskup, Pasquale Striano, Vincenzo Nigro, Mariasavina Severino, Valeria Capra, Gregory Costain, Koh Ichi Nagata
Journal: Brain
PubMed ID: 35851598
Doi: 10.1093/brain/awac106
Products & Services: Custom Vector Construction   
Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma
Authors: Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph Jao-Yiu Sung, Leaf Huang, Rihe Liu, Alfred Sze-Lok Cheng
Journal: Mol Ther
PubMed ID: 36146933
Doi: 10.1016/j.ymthe.2022.09.012
Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis
Authors: Govind Kunduri, Si-Hung Le, Valentina Baena, Nagampalli Vijaykrishna, Adam Harned, Kunio Nagashima, Daniel Blankenberg, Izumi Yoshihiro, Kedar Narayan, Takeshi Bamba, Usha Acharya, Jairaj K Acharya
Journal: PLoS Biol
PubMed ID: 36170207
Doi: 10.1371/journal.pbio.3001599
Products & Services: Custom Vector Construction   
Molecular fate-mapping of serum antibodies reveals the effects of antigenic imprinting on repeated immunization
Authors: Ariën Schiepers, Marije F L van 't Wout, Allison J Greaney, Trinity Zang, Hiromi Muramatsu, Paulo J C Lin, Ying K Tam, Luka Mesin, Tyler N Starr, Paul D Bieniasz, Norbert Pardi, Jesse D Bloom, Gabriel D Victora
Journal: biorxiv
PubMed ID: 36093344
Doi: 10.1101/2022.08.29.505743
Products & Services: Plasmid DNA Preparation   
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