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Thiopurines inhibit coronavirus Spike protein processing and incorporation into progeny virions
Authors: Eric S Pringle, Brett A Duguay, Maxwell P Bui-Marinos, Rory P Mulloy, Shelby L Landreth, Krishna Swaroop Desireddy, Stacia M Dolliver, Shan Ying, Taylor Caddell, Trinity H Tooley, Patrick D Slaine, Stephen L Bearne, Darryl Falzarano, Jennifer A Corcoran, Denys A Khaperskyy, Craig McCormick
Journal: PLoS Pathog
PubMed ID: 36121863
Doi: 10.1371/journal.ppat.1010832
Products & Services: PCR Cloning and Subcloning   
D121 Located within the DRY Motif of P2Y12 Is Essential for P2Y12-Mediated Platelet Function
Authors: Carol Dangelmaier, Benjamin Mauri, Akruti Patel, Satya P Kunapuli, John C Kostyak
Journal: Int J Mol Sci
PubMed ID: 36232816
Doi: 10.3390/ijms231911519
Products & Services: Catalog Peptides   
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein
Authors: Kailu Yang, Chuchu Wang, Alex J B Kreutzberger, Ravi Ojha, Suvi Kuivanen, Sergio Couoh-Cardel, Serena Muratcioglu, Timothy J Eisen, K Ian White, Richard G Held, Subu Subramanian, Kendra Marcus, Richard A Pfuetzner, Luis Esquivies, Catherine A Doyle, John Kuriyan, Olli Vapalahti, Giuseppe Balistreri, Tom Kirchhausen, Axel T Brunger
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36122200
Doi: 10.1073/pnas.2210990119
Products & Services: Peptide Synthesis   
Vaccine target and carrier molecule nontypeable Haemophilus influenzae protein D dimerizes like the close Escherichia coli GlpQ homolog but unlike other known homolog dimers
Authors: Seth P Jones, Kali H Cook, Melody L Holmquist, Liam J Almekinder, Annie M Delaney, Ryhl Charles, Natalie Labbe, Janai Perdue, Niaya Jackson, Michael E Pichichero, Ravinder Kaur, Lea V Michel, Michael L Gleghorn
Journal: Proteins
PubMed ID: 36065600
Doi: 10.1002/prot.26418
Mapping monoclonal anti-SARS-CoV-2 antibody repertoires against diverse coronavirus antigens
Authors: Matheus Oliveira de Souza, Bharat Madan, I-Ting Teng, Aric Huang, Lihong Liu, Ahmed S Fahad, Sheila N Lopez Acevedo, Xiaoli Pan, Mallika Sastry, Matias Gutierrez-Gonzalez, Michael T Yin, Tongqing Zhou, David D Ho, Peter D Kwong, Brandon J DeKosky
Journal: Front Immunol
PubMed ID: 36119018
Doi: 10.3389/fimmu.2022.977064
Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening
Authors: Peter C DeWeirdt, Abby V McGee, Fengyi Zheng, Ifunanya Nwolah, Mudra Hegde, John G Doench
Journal: Nat Commun
PubMed ID: 36068235
Doi: 10.1038/s41467-022-33024-2
Products & Services: Oligo pool   
A recombinant subunit vaccine candidate produced in plants elicits neutralizing antibodies against SARS-CoV-2 variants in macaques
Authors: Narach Khorattanakulchai, Kanjana Srisutthisamphan, Balamurugan Shanmugaraj, Suwimon Manopwisedjaroen, Kaewta Rattanapisit, Chalisa Panapitakkul, Taratorn Kemthong, Nutchanat Suttisan, Suchinda Malaivijitnond, Arunee Thitithanyanont, Anan Jongkaewwattana, Waranyoo Phoolcharoen
Journal: Front Plant Sci
PubMed ID: 36247553
Doi: 10.3389/fpls.2022.901978
Chemoenzymatic Synthesis of SARS-CoV-2 Homogeneous O-Linked Glycopeptides for Exploring Their Inhibition Functions
Authors: Yongheng Rong, Xingyun Wang, Weian Mao, Fang Yuan, Min Chen, Shengjun Wang, Peng George Wang, Zhigang Wu, Yunjiao He, Yun Kong
Journal: ACS Infect Dis
PubMed ID: 36095241
Doi: 10.1021/acsinfecdis.2c00383
Products & Services: Monoclonal Antibody Services   
Herpes Simplex Virus 1 Glycoproteins Differentially Regulate the Activity of Costimulatory Molecules and T Cells
Authors: Harry H Matundan, Ujjaldeep Jaggi, Homayon Ghiasi
Journal: mSphere
PubMed ID: 36094100
Doi: 10.1128/msphere.00382-22
Products & Services: Recombinant Proteins   
A 1-aminocyclopropane-1-carboxylic-acid (ACC) dipeptide elicits ethylene responses through ACC-oxidase mediated substrate promiscuity
Authors: John Vaughan-Hirsch, Dongdong Li, Albert Roig Martinez, Stijn Roden, Jolien Pattyn, Shu Taira, Hitomi Shikano, Yoko Miyama, Yukari Okano, Arnout Voet, Bram Van de Poel
Journal: Front Plant Sci
PubMed ID: 36172554
Doi: 10.3389/fpls.2022.995073
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