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QbD-guided pharmaceutical development of Pembrolizumab biosimilar candidate PSG-024 propelled to industry meeting primary requirements of comparability to Keytruda®
Authors: Morteza Jaffar-Aghaei, Farzad Khanipour, Amir Maghsoudi, Rahim Sarvestani, Mahdi Mohammadian, Maryam Maleki, Forugh Havasi, Hossein Rahmani, Amir-Hossein Karagah, Mohammad-Reza Kazemali
Journal: Eur J Pharm Sci
PubMed ID: 35378209
Doi: 10.1016/j.ejps.2022.106171
Products & Services: Gene Synthesis   
Full-Length Transcriptome Analysis Provides New Insights Into the Diversity of Immune-Related Genes in
Authors: Yi Zhang, Mengqi Ni, Yunhui Bai, Qiao Shi, Jinbin Zheng, Zhaoxia Cui
Journal: Front Immunol
PubMed ID: 35464434
Doi: 10.3389/fimmu.2022.843347
Regulation of Mannitol Metabolism in Enterococcus faecalis and Association with Toxin-Antitoxin Locus Function
Authors: Srivishnupriya Anbalagan, Jessie Sadlon, Keith Weaver
Journal: J Bacteriol
PubMed ID: 35404112
Doi: 10.1128/jb.00047-22
Products & Services: Stable Cell Lines   
The C-terminal extension of VgrG4 from Klebsiella pneumoniae remodels host cell microfilaments
Authors: Talyta do Nascimento Soares, Verônica Silva Valadares, Gisele Cardoso Amorim, Mayara de Mattos Lacerda de Carvalho, Marcia Berrêdo-Pinho, Fábio Ceneviva Lacerda Almeida, Paulo Mascarello Bisch, Paulo Ricardo Batista, Letícia Miranda Santos Lery
Journal: Proteins
PubMed ID: 35430767
Doi: 10.1002/prot.26344
Products & Services: PCR Cloning and Subcloning   
Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4
Authors: Karuna Mittal, Jaspreet Kaur, Shaligram Sharma, Nivya Sharma, Guanhao Wei, Ishita Choudhary, Precious Imhansi-Jacob, Nagini Maganti, Shrikant Pawar, Padmashree Rida, Michael S Toss, Mohammed Aleskandarany, Emiel A Janssen, Håvard Søiland, Meenakshi V Gupta, Michelle D Reid, Emad A Rakha, Ritu Aneja
Journal: Mol Cancer Res
PubMed ID: 34933912
Doi: 10.1158/1541-7786.MCR-20-0798
Products & Services: Plasmid DNA Preparation   
The neural basis of heat seeking in a human-infective parasitic worm
Authors: Astra S Bryant, Felicitas Ruiz, Joon Ha Lee, Elissa A Hallem
Journal: Curr Biol
PubMed ID: 35483361
Doi: 10.1016/j.cub.2022.04.010
Products & Services: Gene Synthesis   
Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans
Authors: Rasheduzzaman Chowdhury, Martine I Abboud, James Wiley, Anthony Tumber, Suzana Markolovic, Christopher J Schofield
Journal: Sci Rep
PubMed ID: 35410347
Doi: 10.1038/s41598-022-10028-y
Products & Services: Custom Vector Construction   
A highly stable human single-domain antibody-drug conjugate exhibits superior penetration and treatment of solid tumors
Authors: Yanling Wu, Quanxiao Li, Yu Kong, Zhi Wang, Cheng Lei, Ji Li, Lulu Ding, Chunyu Wang, Yaping Cheng, Yaozhu Wei, Yuanlin Song, Zhenlin Yang, Chao Tu, Yu Ding, Tianlei Ying
Journal: Mol Ther
PubMed ID: 35462042
Doi: 10.1016/j.ymthe.2022.04.013
Products & Services: Mammalian Expression   
FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P-dependent switch
Authors: Nathan R Zaccai, Zuzana Kadlecova, Veronica Kane Dickson, Kseniya Korobchevskaya, Jan Kamenicky, Oleksiy Kovtun, Perunthottathu K Umasankar, Antoni G Wrobel, Jonathan G G Kaufman, Sally R Gray, Kun Qu, Philip R Evans, Marco Fritzsche, Filip Sroubek, Stefan Höning, John A G Briggs, Bernard T Kelly, David J Owen, Linton M Traub
Journal: Sci Adv
PubMed ID: 35486718
Doi: 10.1126/sciadv.abn2018
Products & Services: Plasmid DNA Preparation   
Distribution of Charged Residues Affects the Average Size and Shape of Intrinsically Disordered Proteins
Authors: Greta Bianchi, Marco Mangiagalli, Alberto Barbiroli, Sonia Longhi, Rita Grandori, Carlo Santambrogio, Stefania Brocca
Journal: Biomolecules
PubMed ID: 35454150
Doi: 10.3390/biom12040561
Products & Services: Custom Vector Construction   
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