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Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
Authors: Chensu Wang, Ang Cui, Maurice Bukenya, Aereas Aung, Dikshant Pradhan, Charles A Whittaker, Yash Agarwal, Ayush Thomas, Simon Liang, Parastoo Amlashi, Heikyung Suh, Stefani Spranger, Nir Hacohen, Darrell J Irvine
Journal: Cell Rep
PubMed ID: 34818534
Doi: 10.1016/j.celrep.2021.110021
Products & Services: Peptide Synthesis   
Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
Authors: In-Chi Young, Bogang Wu, Jaclyn Andricovich, Sung-Ting Chuang, Rong Li, Alexandros Tzatsos, Ray-Chang Wu, Mei-Yi Wu
Journal: Cell Rep
PubMed ID: 34818550
Doi: 10.1016/j.celrep.2021.110036
Products & Services: Plasmid DNA Preparation   
Assessment of in vitro activities of novel modified antimicrobial peptides against clarithromycin resistant Mycobacterium abscessus
Authors: Phantitra Sudadech, Sittiruk Roytrakul, Orawee Kaewprasert, Auttawit Sirichoat, Ploenchan Chetchotisakd, Sakawrat Kanthawong, Kiatichai Faksri
Journal: PLoS ONE
PubMed ID: 34780520
Doi: 10.1371/journal.pone.0260003
Products & Services: Peptide Synthesis   
A molecular dynamics-guided mutagenesis identifies two aspartic acid residues involved in the pH-dependent activity of OG-OXIDASE 1
Authors: Anna Scortica, Matteo Capone, Daniele Narzi, Mario Frezzini, Valentina Scafati, Moira Giovannoni, Francesco Angelucci, Leonardo Guidoni, Benedetta Mattei, Manuel Benedetti
Journal: Plant Physiol Biochem
PubMed ID: 34800821
Doi: 10.1016/j.plaphy.2021.11.011
Products & Services: Gene Synthesis   
Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection
Authors: Henry Daniell, Smruti K Nair, Nardana Esmaeili, Geetanjali Wakade, Naila Shahid, Prem Kumar Ganesan, Md Reyazul Islam, Ariel Shepley-McTaggart, Sheng Feng, Ebony N Gary, Ali R Ali, Manunya Nuth, Selene Nunez Cruz, Jevon Graham-Wooten, Stephen J Streatfield, Ruben Montoya-Lopez, Paul Kaznica, Margaret Mawson, Brian J Green, Robert Ricciardi, Michael Milone, Ronald N Harty, Ping Wang, David B Weiner, Kenneth B Margulies, Ronald G Collman
Journal: Mol Ther
PubMed ID: 34774754
Doi: 10.1016/j.ymthe.2021.11.008
Products & Services: Plasmid DNA Preparation   
Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant
Authors: Ehab Al-Moubarak, Holly A Shiels, Yihong Zhang, Chunyun Du, Oliver Hanington, Stephen C Harmer, Christopher E Dempsey, Jules C Hancox
Journal: Cell Mol Life Sci
PubMed ID: 34727194
Doi: 10.1007/s00018-021-03967-8
Products & Services: Gene Synthesis   
The σ1 Receptor and the HINT1 Protein Control α2δ1 Binding to Glutamate NMDA Receptors: Implications in Neuropathic Pain
Authors: María Rodríguez-Muñoz, Elsa Cortés-Montero, Yara Onetti, Pilar Sánchez-Blázquez, Javier Garzón-Niño
Journal: Biomolecules
PubMed ID: 34827679
Doi: 10.3390/biom11111681
Products & Services: Catalog Antibody   
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors
Authors: Teklab Gebregiworgis, Yoshihito Kano, Jonathan St-Germain, Nikolina Radulovich, Molly L Udaskin, Ahmet Mentes, Richard Huang, Betty P K Poon, Wenguang He, Ivette Valencia-Sama, Claire M Robinson, Melissa Huestis, Jinmin Miao, Jen Jen Yeh, Zhong-Yin Zhang, Meredith S Irwin, Jeffrey E Lee, Ming-Sound Tsao, Brian Raught, Christopher B Marshall, Michael Ohh, Mitsuhiko Ikura
Journal: Nat Commun
PubMed ID: 34725361
Doi: 10.1038/s41467-021-26526-y
Products & Services: Bacterial Expression   
Formation of nuclear condensates by the Mediator complex subunit Med15 in mammalian cells
Authors: Yuanyuan Shi, Jian Chen, Wei-Jie Zeng, Miao Li, Wenxue Zhao, Xing-Ding Zhang, Jie Yao
Journal: BMC Biol
PubMed ID: 34789250
Doi: 10.1186/s12915-021-01178-y
Products & Services: Gene Synthesis   
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