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Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen

Authors: Zaid Taha, Rozanne Arulanandam, Glib Maznyi, Elena Godbout, Madalina E Carter-Timofte, Naziia Kurmasheva, Line S Reinert, Andrew Chen, Mathieu J F Crupi, Stephen Boulton, Geneviève Laroche, Alexandra Phan, Reza Rezaei, Nouf Alluqmani, Anna Jirovec, Alexandra Acal, Emily E F Brown, Ragunath Singaravelu, Julia Petryk, Manja Idorn, Kyle G Potts, Hayley Todesco, Cini John, Douglas J Mahoney, Carolina S Ilkow, Patrick Giguère, Tommy Alain, Marceline Côté, Søren R Paludan, David Olagnier, John C Bell, Taha Azad, Jean-Simon Diallo

Journal: Mol Ther

PubMed ID: 35526097

Doi: 10.1016/j.ymthe.2022.04.025

Products & Services: Mammalian Expression

BpEIN31 represses leaf senescence by inhibiting synthesis of ethylene and abscisic acid in Betula platyphylla

Authors: Shiyu Song, Mengyan Ge, Wei Wang, Chenrui Gu, Kun Chen, Qingzhu Zhang, Qibin Yu, Guifeng Liu, Jing Jiang

Journal: Plant Sci

PubMed ID: 35696929

Doi: 10.1016/j.plantsci.2022.111330

Products & Services: Protein Tools

Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine

Authors: Shigehiro Tsukahara, Masaki Shiota, Dai Takamatsu, Shohei Nagakawa, Takashi Matsumoto, Ryo Kiyokoba, Mikako Yagi, Daiki Setoyama, Nozomi Noda, Shinya Matsumoto, Tetsutaro Hayashi, Alberto Contreras-Sanz, Peter C Black, Junichi Inokuchi, Kenichi Kohashi, Yoshinao Oda, Takeshi Uchiumi, Masatoshi Eto, Dongchon Kang

Journal: Sci Rep

PubMed ID: 35595780

Doi: 10.1038/s41598-022-12528-3

Products & Services: Mutagenesis Services

LncRNA JPX Promotes Esophageal Squamous Cell Carcinoma Progression by Targeting miR-516b-5p/VEGFA Axis

Authors: Yi He, Rong Hua, Yang Yang, Bin Li, Xufeng Guo, Zhigang Li

Journal: Cancers (Basel)

PubMed ID: 35681693

Doi: 10.3390/cancers14112713

Products & Services: Custom Vector Construction

Analysis of rhodopsin G protein-coupled receptor orthologs reveals semiochemical peptides for parasite (Schistosoma mansoni) and host (Biomphalaria glabrata) interplay

Authors: Phong Phan, Di Liang, Min Zhao, Russell C Wyeth, Conor Fogarty, Mary G Duke, Donald P McManus, Tianfang Wang, Scott F Cummins

Journal: Sci Rep

PubMed ID: 35581232

Doi: 10.1038/s41598-022-11996-x

Products & Services: Catalog Antibody

Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses

Authors: Brendan Beaton, Sarah C Sasson, Katherine Rankin, Juliette Raedemaeker, Alexander Wong, Priyanka Hastak, Chansavath Phetsouphanh, Andrew Warden, Vera Klemm, C Mee Ling Munier, Alexandra Carey Hoppe, Fiona Tea, Aleha Pillay, Alberto Ospina Stella, Anupriya Aggarwal, Orly Lavee, Ian D Caterson, Stuart Turville, Anthony D Kelleher, Fabienne Brilot, Judith Trotman

Journal: Am J Hematol

PubMed ID: 35607995

Doi: 10.1002/ajh.26619

Products & Services: Catalog Peptides

Discovery and functional assessment of a novel adipocyte population driven by intracellular Wnt/β-catenin signaling in mammals

Authors: Zhi Liu, Tian Chen, Sicheng Zhang, Tianfang Yang, Yun Gong, Hong-Wen Deng, Ding Bai, Weidong Tian, YiPing Chen

Journal: Elife

PubMed ID: 35503096

Doi: 10.7554/eLife.77740

Products & Services: Molecular Biology Reagents

Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3

Authors: Qing Zhang, Jun Ren, Fangfang Wang, Manman Pan, Long Cui, Mingqian Li, Fan Qu