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GAPDH mediates plant reovirus-induced incomplete autophagy for persistent viral infection in leafhopper vector

Authors: Qian Chen, Yuele Zhang, Hengsong Yang, Xin Wang, Jiping Ren, Dongsheng Jia, Hongyan Chen, Taiyun Wei

Journal: Autophagy

PubMed ID: 36036160

Doi: 10.1080/15548627.2022.2115830

Products & Services: Polyclonal Antibody Services

Conformational buffering underlies functional selection in intrinsically disordered protein regions

Authors: Nicolás S González-Foutel, Juliana Glavina, Wade M Borcherds, Matías Safranchik, Susana Barrera-Vilarmau, Amin Sagar, Alejandro Estaña, Amelie Barozet, Nicolás A Garrone, Gregorio Fernandez-Ballester, Clara Blanes-Mira, Ignacio E Sánchez, Gonzalo de Prat-Gay, Juan Cortés, Pau Bernadó, Rohit V Pappu, Alex S Holehouse, Gary W Daughdrill, Lucía B Chemes

Journal: Nat Struct Mol Biol

PubMed ID: 35948766

Doi: 10.1038/s41594-022-00811-w

Products & Services: Catalog Peptides

Identification of linear epitopes and their major role in the immunoglobulin E-binding capacity of tropomyosin from

Authors: Nai-Ru Ji, Xin-Yu Han, Chen-Chen Yu, Xin-Rong He, Shi-Tao Rao, Fei Huan, Hong Liu, Gui-Xia Chen, Min-Jie Cao, Guang-Ming Liu

Journal: Food Funct

PubMed ID: 35943407

Doi: 10.1039/d2fo01713j

Products & Services: Peptide Synthesis

Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domain

Authors: Jing-Yi Zhou, Rui-Rui Yang, Jie Chang, Jia Song, Zi-Sheng Fan, Ying-Hui Zhang, Cheng-Hao Lu, Hua-Liang Jiang, Ming-Yue Zheng, Su-Lin Zhang

Journal: Acta Pharmacol Sin

PubMed ID: 35918411

Doi: 10.1038/s41401-022-00936-0

Products & Services: Catalog Antibody

AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling

Authors: Renata Ferrarotto, Vasudha Mishra, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch, Adi Mondshine, Maria Motin, Tal Leibovich-Rivkin, Matti Davis, Joel Kaye, Christopher R Weber, Le Shen, Alexander T Pearson, Ari J Rosenberg, Xiangying Chen, Alka Singh, Jon C Aster, Nishant Agrawal, Evgeny Izumchenko

Journal: Cell Death Dis

PubMed ID: 35931701

Doi: 10.1038/s41419-022-05133-9

Products & Services: Mammalian Expression

Oral glucagon-like peptide 1 analogue ameliorates glucose intolerance in db/db mice

Authors: Hanlin Zhang, Meng Dong, Shouli Yuan, Wanzhu Jin

Journal: Biotechnol Lett

PubMed ID: 36006576

Doi: 10.1007/s10529-022-03288-1

Products & Services: Peptide Synthesis

A Localized Materials-Based Strategy to Non-Virally Deliver Chondroitinase ABC mRNA Improves Hindlimb Function in a Rat Spinal Cord Injury Model

Authors: Andrew S Khalil, Daniel Hellenbrand, Kaitlyn Reichl, Jennifer Umhoefer, Mallory Filipp, Joshua Choe, Amgad Hanna, William L Murphy

Journal: Adv Healthc Mater

PubMed ID: 35882512

Doi: 10.1002/adhm.202200206

Products & Services: Plasmid DNA Preparation

The NCF1 variant pR90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells

Authors: Yao Meng, Jianyang Ma, Chao Yao, Zhizhong Ye, Huihua Ding, Can Liu, Jun Li, Guanhua Li, Yuke He, Jia Li, Zhihua Yin, Li Wu, Haibo Zhou, Nan Shen

Journal: J Clin Invest

PubMed ID: 35788118

Doi: 10.1172/JCI153619

Products & Services: Proteins, Expression, Isolation and Analysis

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

Authors: Rani Burm, Panagiota Maravelia, Gustaf Ahlen, Sandra Ciesek, Noelia Caro Perez, Anna Pasetto, Stephan Urban, Freya Van Houtte, Lieven Verhoye, Heiner Wedemeyer, Magnus Johansson, Lars Frelin, Matti Sällberg, Philip Meuleman

Journal: Gut

PubMed ID: 35977815

Doi: 10.1136/gutjnl-2022-327216

Products & Services: Proteins, Expression, Isolation and Analysis

mmu-microRNA-92a-3p attenuates pulmonary fibrosis by modulating Cpeb4-mediated Smad2/3 signaling pathway

Authors: Mengkun Shi, Huixia Cui, Jialun Shi, Yunqing Mei

Journal: Funct Integr Genomics

PubMed ID: 35909199

Doi: 10.1007/s10142-022-00879-z

Products & Services: Mutant Libraries

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