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Leveraging the multivalent p53 peptide-MdmX interaction to guide the improvement of small molecule inhibitors
Authors: Xiyao Cheng, Rong Chen, Ting Zhou, Bailing Zhang, Zichun Li, Meng Gao, Yongqi Huang, Huili Liu, Zhengding Su
Journal: Nat Commun
PubMed ID: 35228542
Doi: 10.1038/s41467-022-28721-x
Products & Services: Plasmid DNA Preparation   
Reduced α-galactosidase A activity in zebrafish ( mirrors distinct features of Fabry nephropathy phenotype
Authors: Hassan O A Elsaid, Jessica Furriol, Maria Blomqvist, Mette Diswall, Sabine Leh, Naouel Gharbi, Jan Haug Anonsen, Janka Babickova, Camilla Tøndel, Einar Svarstad, Hans-Peter Marti, Maximilian Krause
Journal: Mol Genet Metab Rep
PubMed ID: 35242583
Doi: 10.1016/j.ymgmr.2022.100851
Products & Services: Catalog Antibody   
Characterization of a Group of UDP-Glycosyltransferases Involved in the Biosynthesis of Triterpenoid Saponins of
Authors: Yanting Li, Jianxiu Li, Mengxue Diao, Longyun Peng, Shihai Huang, Nengzhong Xie
Journal: ACS Synth Biol
PubMed ID: 35107265
Doi: 10.1021/acssynbio.1c00469
Products & Services: Gene Synthesis   
miR-AB, a miRNA-based shRNA viral toolkit for multicolor-barcoded multiplex RNAi at a single-cell level
Authors: Dapeng Wang, Jianbo Xiu, Jiangyue Zhao, Junli Luo
Journal: EMBO Rep
PubMed ID: 35201651
Doi: 10.15252/embr.202153691
Products & Services: Custom DNA/RNA Oligos   
Changes in Non-Deamidated versus Deamidated Epitope Targeting and Disease Prediction during the Antibody Response to Gliadin and Transglutaminase of Infants at Risk for Celiac Disease
Authors: Ádám Diós, Bharani Srinivasan, Judit Gyimesi, Katharina Werkstetter, Rudolf Valenta, Sibylle Koletzko, Ilma R Korponay-Szabó
Journal: Int J Mol Sci
PubMed ID: 35269639
Doi: 10.3390/ijms23052498
Products & Services: Catalog Peptides   
Poly(ADP-ribose) drives condensation of FUS via a transient interaction
Authors: Kevin Rhine, Morgan Dasovich, Joseph Yoniles, Mohsen Badiee, Sophie Skanchy, Laura R Ganser, Yingda Ge, Charlotte M Fare, James Shorter, Anthony K L Leung, Sua Myong
Journal: Mol Cell
PubMed ID: 35182479
Doi: 10.1016/j.molcel.2022.01.018
Products & Services: Plasmid DNA Preparation   
Affibody Modified G-quadruplex DNA Micelles Incorporating Polymeric 5-Fluorodeoxyuridine for Targeted Delivery of Curcumin to Enhance Synergetic Therapy of HER2 Positive Gastric Cancer
Authors: Chao Zhang, Shuangqing Fu, Fanghua Zhang, Mengnan Han, Xuming Wang, Jie Du, Honglei Zhang, Wei Li
Journal: Nanomaterials (Basel)
PubMed ID: 35215023
Doi: 10.3390/nano12040696
Products & Services: Custom DNA/RNA Oligos   
KIF18B promotes breast cancer cell proliferation, migration and invasion by targeting TRIP13 and activating the Wnt/β-catenin signaling pathway
Authors: Lan Liu, Zhaofeng Zhang, Xiulin Xia, Jing Lei
Journal: Oncol Lett
PubMed ID: 35251343
Doi: 10.3892/ol.2022.13232
Products & Services: Custom Vector Construction   
A CRISPR-based nucleic acid detection method for severe fever with thrombocytopenia syndrome virus
Authors: Yansong Zhang, Xuanyang Bai, Jinhui Li, Jing Xie, Huan Li, Lang Yang, Peihan Li, Peng Li, Hao Dong, Qichao Chen, Xinyan Hu, Yun Wang, Tingting Jiang, Hongbin Song, Leili Jia, Lizhong Li
Journal: Virus Res
PubMed ID: 35143909
Doi: 10.1016/j.virusres.2022.198691
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Authors: Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, Yingxiao Zhu, Xiaodong Yan, Hui Shi, François Ferron, Bruno Canard
Journal: Nat Commun
PubMed ID: 35110538
Doi: 10.1038/s41467-022-28113-1
Products & Services: Custom DNA/RNA Oligos   
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