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RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants

Authors: Qingtai Liang, Yifeng Wang, Shuyuan Zhang, Jing Sun, Wenbo Sun, Jizhou Li, Yaping Liu, Mingxi Li, Lin Cheng, Yuhang Jiang, Ruoke Wang, Rui Zhang, Zihan Yang, Yifei Ren, Peng Chen, Peng Gao, Huayuan Yan, Zheng Zhang, Qi Zhang, Xuanling Shi, Jianbin Wang, Wanli Liu, Xinquan Wang, Bo Ying, Jincun Zhao, Hai Qi, Linqi Zhang

Journal: iScience

PubMed ID: 35291264

Doi: 10.1016/j.isci.2022.104043

Products & Services: Catalog Peptides

AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition

Authors: Yongchao Xie, Laixing Zhang, Zhengyu Gao, Peipei Yin, Hao Wang, Hang Li, Zeliang Chen, Yi Zhang, Maojun Yang, Yue Feng

Journal: Nat Chem Biol

PubMed ID: 35301482

Doi: 10.1038/s41589-022-00995-8

Products & Services: PCR and Cloning

RACK1 Associates with RNA-Binding Proteins Vigilin and SERBP1 to Facilitate Dengue Virus Replication

Authors: Alexis Brugier, Mohamed Lamine Hafirrassou, Marie Pourcelot, Morgane Baldaccini, Vasiliya Kril, Laurine Couture, Beate M Kümmerer, Sarah Gallois-Montbrun, Lucie Bonnet-Madin, Pierre-Olivier Vidalain, Constance Delaugerre, Sébastien Pfeffer, Laurent Meertens, Ali Amara

Journal: J Virol

PubMed ID: 35266803

Doi: 10.1128/jvi.01962-21

Products & Services: Mammalian Expression

FSH blockade improves cognition in mice with Alzheimer's disease

Authors: Jing Xiong, Seong Su Kang, Zhihao Wang, Xia Liu, Tan-Chun Kuo, Funda Korkmaz, Ashley Padilla, Sari Miyashita, Pokman Chan, Zhaohui Zhang, Pavel Katsel, Jocoll Burgess, Anisa Gumerova, Kseniia Ievleva, Damini Sant, Shan-Ping Yu, Valeriia Muradova, Tal Frolinger, Daria Lizneva, Jameel Iqbal, Ki A Goosens, Sakshi Gera, Clifford J Rosen, Vahram Haroutunian, Vitaly Ryu, Tony Yuen, Mone Zaidi, Keqiang Ye

Journal: Nature

PubMed ID: 35236988

Doi: 10.1038/s41586-022-04463-0

Products & Services: Gene Synthesis

Protein Electrostatics Investigated through Paramagnetic NMR for Nonpolar Groups

Authors: Binhan Yu, Channing C Pletka, Junji Iwahara

Journal: J Phys Chem B

PubMed ID: 35266708

Doi: 10.1021/acs.jpcb.1c10930

Products & Services: Mammalian Expression

Melatonin Regulates Lipid Metabolism in Porcine Cumulus-Oocyte Complexes via the Melatonin Receptor 2

Authors: Jun-Xue Jin, Jing-Tao Sun, Chao-Qian Jiang, Hong-Di Cui, Ya Bian, Sanghoon Lee, Lianjin Zhang, Byeong Chun Lee, Zhong-Hua Liu

Journal: Antioxidants (Basel)

PubMed ID: 35453372

Doi: 10.3390/antiox11040687

Products & Services: Proteins, Expression, Isolation and Analysis

Albumin Nanoparticle Endocytosing Subset of Neutrophils for Precision Therapeutic Targeting of Inflammatory Tissue Injury

Authors: Kurt Bachmaier, Andrew Stuart, Abhalaxmi Singh, Amitabha Mukhopadhyay, Sreeparna Chakraborty, Zhigang Hong, Li Wang, Yoshikazu Tsukasaki, Mark Maienschein-Cline, Balaji B Ganesh, Prasad Kanteti, Jalees Rehman, Asrar B Malik

Journal: ACS Nano

PubMed ID: 35230826

Doi: 10.1021/acsnano.1c09762

Products & Services: Endotoxin Detection & Removal System

Systematic Discovery of FBXW7-Binding Phosphodegrons Highlights Mitogen-Activated Protein Kinases as Important Regulators of Intracellular Protein Levels

Authors: Neha Singh, András Zeke, Attila Reményi

Journal: Int J Mol Sci

PubMed ID: 35328741

Doi: 10.3390/ijms23063320

Products & Services: Custom Vector Construction

Neddylation is essential for β-catenin degradation in Wnt signaling pathway

Authors: Bojun Wang, Tiantian Wang, Huimin Zhu, Rong Yan, Xinru Li, Chengqian Zhang, Wanyu Tao, Xisong Ke, Piliang Hao, Yi Qu