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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells

Authors: Shreyasi Mukherjee, David M Luedeke, Leslie McCoy, Makiko Iwafuchi, Aaron M Zorn

Journal: Cell Rep

PubMed ID: 36001974

Doi: 10.1016/j.celrep.2022.111247

Products & Services: Custom Vector Construction

Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors

Authors: Sanghyun P Kim, Nolan R Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C Deniger, Frank J Lowery, Maria R Parkhurst, Lien T Ngo, Satyajit Ray, Yong F Li, Victoria Hill, Maria Florentin, Robert V Masi, Biman C Paria, Noam Levin, Alakesh Bera, Elizabeth A Hedges, Agnes Choi, Praveen D Chatani, Anup Y Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D Prickett, Li Jia, Jonathan M Hernandez, Chuong D Hoang, Paul F Robbins, Stephanie L Goff, Richard M Sherry, James C Yang, Steven A Rosenberg

Journal: Cancer Immunol Res

PubMed ID: 35749374

Doi: 10.1158/2326-6066.CIR-22-0040

Products & Services: Peptide Synthesis

Optimized production and fluorescent labeling of SARS-CoV-2 virus-like particles

Authors: Manon Gourdelier, Jitendriya Swain, Coline Arone, Anita Mouttou, David Bracquemond, Peggy Merida, Saveez Saffarian, Sébastien Lyonnais, Cyril Favard, Delphine Muriaux

Journal: Sci Rep

PubMed ID: 36030323

Doi: 10.1038/s41598-022-18681-z

Products & Services: Plasmid DNA Preparation

Evolutionary adaptation of the protein folding pathway for secretability

Authors: Dries Smets, Alexandra Tsirigotaki, Jochem H Smit, Srinath Krishnamurthy, Athina G Portaliou, Anastassia Vorobieva, Wim Vranken, Spyridoula Karamanou, Anastassios Economou

Journal: EMBO J

PubMed ID: 36031863

Doi: 10.15252/embj.2022111344

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Disruption of nuclear envelope integrity as a possible initiating event in tauopathies

Authors: Marine Prissette, Wen Fury, Matthew Koss, Claudia Racioppi, Daria Fedorova, Ella Dragileva, Georgia Clarke, Taylor Pohl, John Dugan, Diana Ahrens, Joyce Chiu, Charleen Hunt, Chia-Jen Siao, Tara Young, Arijit Bhowmick, Vitaliy Rogulin, Mathieu Desclaux, Eric Y Hayden, Michael Podgorski, Min Gao, Lynn E Macdonald, David Frendewey, George D Yancopoulos, Brian Zambrowicz

Journal: Cell Rep

PubMed ID: 36001963

Doi: 10.1016/j.celrep.2022.111249

Products & Services: Synthetic sgRNA and crRNA Service

Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System

Authors: Timothy A Klein, Dirk W Grebenc, Prakhar Y Shah, Owen D McArthur, Brandon H Dickson, Michael G Surette, Youngchang Kim, John C Whitney

Journal: MBio

PubMed ID: 36036513

Doi: 10.1128/mbio.02137-22

Products & Services: Polyclonal Antibody Services

USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation

Authors: Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire, Veronique A J Smits

Journal: Cells

PubMed ID: 36010569

Doi: 10.3390/cells11162492

Products & Services: Proteins, Expression, Isolation and Analysis

Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency

Authors: Zhipeng Ai, Xinyu Xiang, Yangquan Xiang, Iwona Szczerbinska, Yuli Qian, Xiao Xu, Chenyang Ma, Yaqi Su, Bing Gao, Hao Shen, Muhammad Nadzim Bin Ramli, Di Chen, Yue Liu, Jia-Jie Hao, Huck Hui Ng, Dan Zhang, Yun-Shen Chan, Wanlu Liu, Hongqing Liang

Journal: Cell Rep

PubMed ID: 36001968

Doi: 10.1016/j.celrep.2022.111240

Products & Services: Catalog Antibody

Case report: A novel loss-of-function pathogenic variant in the KCNA1 cytoplasmic N-terminus causing carbamazepine-responsive type 1 episodic ataxia

Authors: Rían W Manville, Richard Sidlow, Geoffrey W Abbott

Journal: Front Neurol

PubMed ID: 36016548

Doi: 10.3389/fneur.2022.975849

Products & Services: Custom Vector Construction

LIMP2 gene, evolutionarily conserved regulation by TFE3, relieves lysosomal stress induced by cholesterol

Authors: Hanze Guo, Yingying Zhu, Jiarui Li, Qipeng Zhang, Yan Chi

Journal: Life Sci

PubMed ID: 35987341

Doi: 10.1016/j.lfs.2022.120888

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