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Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action
Authors: Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A Zubarev, Stig Linder, Pádraig D'Arcy
Journal: Front Oncol
PubMed ID: 35530310
Doi: 10.3389/fonc.2022.852980
Products & Services: Oligo pool   
Combination of resolvin E1 and lipoxin A4 promotes the resolution of pulpitis by inhibiting NF-κB activation through upregulating sirtuin 7 in dental pulp fibroblasts
Authors: Xiaochen Liu, Chunmeng Wang, Liping Pang, Liangliang Pan, Qi Zhang
Journal: Cell Prolif
PubMed ID: 35411569
Doi: 10.1111/cpr.13227
Products & Services: Recombinant Proteins   
The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption
Authors: Sachin Wani, Anna Daroszewska, Donald M Salter, Rob J van 't Hof, Stuart H Ralston, Omar M E Albagha
Journal: Dis Model Mech
PubMed ID: 35229101
Doi: 10.1242/dmm.049318
Products & Services: Plasmid DNA Preparation   
Recombinant human N-acetylneuraminate lyase as a tool to study clinically relevant mutant variants
Authors: Cheng Cheng, Zi-Xuan Hu, Meng He, Li Liu, Josef Voglmeir
Journal: Carbohydr Res
PubMed ID: 35487178
Doi: 10.1016/j.carres.2022.108561
Products & Services: Mammalian Expression   
CLEVER assay: A visual and rapid RNA extraction-free detection of SARS-CoV-2 based on CRISPR-Cas integrated RT-LAMP technology
Authors: Akansha Bhatt, Zeeshan Fatima, Munindra Ruwali, Chitra Seetharam Misra, Shyam Sunder Rangu, Devashish Rath, Ashok Rattan, Saif Hameed
Journal: J Appl Microbiol
PubMed ID: 35396760
Doi: 10.1111/jam.15571
Products & Services: Plasmid DNA Preparation   
Insect Cells for High-Yield Production of SARS-CoV-2 Spike Protein: Building a Virosome-Based COVID-19 Vaccine Candidate
Authors: Bárbara Fernandes, Rute Castro, Farien Bhoelan, Denzel Bemelman, Ricardo A Gomes, Júlia Costa, Patrícia Gomes-Alves, Toon Stegmann, Mario Amacker, Paula M Alves, Sylvain Fleury, António Roldão
Journal: Pharmaceutics
PubMed ID: 35456687
Doi: 10.3390/pharmaceutics14040854
Products & Services: Plasmid DNA Preparation   
G-protein biased signaling agonists of Dopamine D3 receptor promote distinct activation patterns of ERK1/2
Authors: Wei Xu, Frank Bearoff, Sandhya Kortagere
Journal: Pharmacol Res
PubMed ID: 35429668
Doi: 10.1016/j.phrs.2022.106223
A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models
Authors: Anurupa A Ghosh, Dinesh Kumar Verma, Gabriela Cabrera, Kwadwo Ofori, Karina Hernandez-Quijada, Jae-Kwan Kim, Joo Hee Chung, Michael Moore, Sung Hwan Moon, Jong Bok Seo, Yong-Hwan Kim
Journal: Int J Mol Sci
PubMed ID: 35457082
Doi: 10.3390/ijms23084262
Identification of Single-Molecule Catecholamine Enantiomers Using a Programmable Nanopore
Authors: Wendong Jia, Chengzhen Hu, Yuqin Wang, Yao Liu, Liying Wang, Shanyu Zhang, Qiang Zhu, Yuming Gu, Panke Zhang, Jing Ma, Hong-Yuan Chen, Shuo Huang
Journal: ACS Nano
PubMed ID: 35394745
Doi: 10.1021/acsnano.2c01017
Products & Services: Gene Synthesis   
A Nanopore Based Molnupiravir Sensor
Authors: Wendong Jia , Chengzhen Hu , Yuqin Wang , Panke Zhang , Hong-Yuan Chen , Shuo Huang
Journal: ACS Sens
PubMed ID: 35427117
Doi: 10.1021/acssensors.2c00447
Products & Services: Plasmid DNA Preparation   
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