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Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes
Authors: Ayesa Syenina, Esther S Gan, Justin Z N Toh, Ruklanthi de Alwis, Lowell Z Lin, Christine Y L Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L E Wee, Dorothy H L Ng, Kuan Rong Chan, Jean X Y Sim, Shirin Kalimuddin, Eugenia Z Ong, Jenny G Low, Eng Eong Ooi
Journal: PLoS Biol
PubMed ID: 35639676
Doi: 10.1371/journal.pbio.3001643
SEC is an antiangiogenic virulence factor that promotes endocarditis independent of superantigen activity
Authors: Kyle J Kinney, Sharon S Tang, Xiao-Jun Wu, Phuong M Tran, Nikhila S Bharadwaj, Katherine N Gibson-Corley, Ana N Forsythe, Katarina Kulhankova, Jenny E Gumperz, Wilmara Salgado-Pabón
Journal: Sci Adv
PubMed ID: 35544579
Doi: 10.1126/sciadv.abo1072
Products & Services: Gene Synthesis   
High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA1
Authors: Maria Kuzikov, Jannis Woens, Andrea Zaliani, Julia Hambach, Thomas Eden, Boris Fehse, Bernhard Ellinger, Kristoffer Riecken
Journal: Biomed Pharmacother
PubMed ID: 35643072
Doi: 10.1016/j.biopha.2022.113104
Products & Services: Plasmid DNA Preparation   
Scalable biological signal recording in mammalian cells using Cas12a base editors
Authors: Hannah R Kempton, Kasey S Love, Lucie Y Guo, Lei S Qi
Journal: Nat Chem Biol
PubMed ID: 35637351
Doi: 10.1038/s41589-022-01034-2
Two Liberibacter Proteins Combine to Suppress Critical Innate Immune Defenses in Citrus
Authors: Supratim Basu, Loan Huynh, Shujian Zhang, Roel Rabara, Hau Nguyen, Jeanette Velásquez Guzmán, Guixia Hao, Godfrey Miles, Qingchun Shi, Ed Stover, Goutam Gupta
Journal: Front Plant Sci
PubMed ID: 35586217
Doi: 10.3389/fpls.2022.869178
Products & Services: PCR Cloning and Subcloning   
Characterization and clustering of kinase isoform expression in metastatic melanoma
Authors: David O Holland, Valer Gotea, Kevin Fedkenheuer, Sushil K Jaiswal, Catherine Baugher, Hua Tan, Michael Fedkenheuer, Laura Elnitski
Journal: PLoS Comput Biol
PubMed ID: 35560144
Doi: 10.1371/journal.pcbi.1010065
Products & Services: Gene Synthesis   
Convergent Alterations of a Protein Hub Produce Divergent Effects within a Binding Site
Authors: Ali Imran, Brandon S Moyer, Dan Kalina, Thomas M Duncan, Kelsey J Moody, Aaron J Wolfe, Michael S Cosgrove, Liviu Movileanu
Journal: ACS Chem Biol
PubMed ID: 35613319
Doi: 10.1021/acschembio.2c00273
The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer
Authors: Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E Ivanova, Kathryn M Stevens, Alex Montoya, S Sunidhi, Nicolas Lopez Carranza, Marcin J Skwark, Christian Speck
Journal: Nat Commun
PubMed ID: 35614055
Doi: 10.1038/s41467-022-30576-1
Products & Services: Mutant Libraries   
Correlation Analysis of Anti-SARS-CoV-2 RBD IgG and Neutralizing Antibody against SARS-CoV-2 Omicron Variants after Vaccination
Authors: Nuchjira Takheaw, Chalerm Liwsrisakun, Warawut Chaiwong, Witida Laopajon, Supansa Pata, Juthamas Inchai, Pilaiporn Duangjit, Chaicharn Pothirat, Chaiwat Bumroongkit, Athavudh Deesomchok, Theerakorn Theerakittikul, Atikun Limsukon, Pattraporn Tajarernmuang, Nutchanok Niyatiwatchanchai, Konlawij Trongtrakul, Watchara Kasinrerk
Journal: Diagnostics (Basel)
PubMed ID: 35741126
Doi: 10.3390/diagnostics12061315
Klotho-derived peptide 6 ameliorates diabetic kidney disease by targeting Wnt/b-catenin signaling
Authors: Xiaowen Chen , Huishi Tan , Jie Xu , Yuan Tian , Qian Yuan , Yangyang Zuo , Qiyan Chen , Xue Hong , Haiyan Fu , Fan Fan Hou , Lili Zhou , Youhua Liu
Journal: Kidney Int
PubMed ID: 35644285
Doi: 10.1016/j.kint.2022.04.028
Products & Services: Peptide Synthesis   
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