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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 40/4751 每页显示数量

A glutamine-based single α-helix scaffold to target globular proteins

Authors: Albert Escobedo, Jonathan Piccirillo, Juan Aranda, Tammo Diercks, Borja Mateos, Carla Garcia-Cabau, Macarena Sánchez-Navarro, Busra Topal, Mateusz Biesaga, Lasse Staby, Birthe B Kragelund, Jesús García, Oscar Millet, Modesto Orozco, Murray Coles, Ramon Crehuet, Xavier Salvatella

Journal: Nat Commun

PubMed ID: 36400768

Doi: 10.1038/s41467-022-34793-6

Products & Services: Peptide Synthesis

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Authors: Liang Chen, Biyun Zhu, Gaomeng Ru, Haowei Meng, Yongchang Yan, Mengjia Hong, Dan Zhang, Changming Luan, Shun Zhang, Hao Wu, Hongyi Gao, Sijia Bai, Changqing Li, Ruoyi Ding, Niannian Xue, Zhixin Lei, Yuting Chen, Yuting Guan, Stefan Siwko, Yiyun Cheng, Gaojie Song, Liren Wang, Chengqi Yi, Mingyao Liu, Dali Li

Journal: Nat Biotechnol

PubMed ID: 36357717

Doi: 10.1038/s41587-022-01532-7

Products & Services: Synthetic sgRNA and crRNA Service

Fitness Costs of pfhrp2 and pfhrp3 Deletions Underlying Diagnostic Evasion in Malaria Parasites

Authors: Shalini Nair, Xue Li, Standwell C Nkhoma, Tim Anderson

Journal: J Infect Dis

PubMed ID: 35709327

Doi: 10.1093/infdis/jiac240

Products & Services: Plasmid DNA Preparation

Sequestration of a dual function DNA-binding protein by Vibrio cholerae CRP

Authors: Jacob A Gibson, Michael J Gebhardt, Renato E R S Santos, Simon L Dove, Paula I Watnick

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36343262

Doi: 10.1073/pnas.2210115119

Products & Services: Monoclonal Antibody Services

Structure-based engineering of minimal Proline dehydrogenase domains for inhibitor discovery

Authors: Alexandra N Bogner, Juan Ji, John J Tanner

Journal: Protein Eng Des Sel

PubMed ID: 36448708

Doi: 10.1093/protein/gzac016

Products & Services: Plasmids for SARS-CoV-2 Detection and Research

PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM restriction

Authors: Mingtian Zhong , Kaizhao Chen , Wenjun Sun , Xiangyang Li , Shisheng Huang , Qingzhou Meng , Bo Sun , Xingxu Huang , Xinjie Wang , Xiaodong Ma , Peixiang Ma

Journal: Biosens Bioelectron

PubMed ID: 35797934

Doi: 10.1016/j.bios.2022.114497

Products & Services: Gene Synthesis

A switchable Cas12a enabling CRISPR-based direct histone deacetylase activity detection

Authors: Wenyuan Kang , Lin Liu , Peihang Yu , Tianyi Zhang , Chunyang Lei , Zhou Nie

Journal: Biosens Bioelectron

PubMed ID: 35700604

Doi: doi.org/10.1016/j.bios.2022.114468

Products & Services: Gene Synthesis

Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium

Authors: Yunzhe Lu , Ruolan Deng , Huanyang You , Yishu Xu , Christopher Antos , Jianlong Sun , Ophir D Klein , Pengfei Lu

Journal: Cell Rep

PubMed ID: 33053348

Doi: 10.1016/j.celrep.2020.108246

Products & Services: Recombinant Proteins

Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone

Authors: Yongrui Liu , Yue Li , Hongyu Bao , Yanhong Liu , Liu Chen , Hongda Huang

Journal: J Mol Biol

PubMed ID: 35870648

Doi: 10.1016/j.jmb.2022.167756

Products & Services: Gene Synthesis

De novo design of anti-tuberculosis agents using a structure-based deep learning method

Authors: Sowmya Ramaswamy Krishnan, Navneet Bung, Siladitya Padhi, Gopalakrishnan Bulusu, Parimal Misra, Manojit Pal, Srinivas Oruganti, Rajgopal Srinivasan, Arijit Roy

Journal: J Mol Graph Model

PubMed ID: 36257148

Doi: 10.1016/j.jmgm.2022.108361

Products & Services: Plasmid DNA Preparation

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