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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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Low specific growth rate and temperature in fed-batch cultures of a beta-propeller phytase producing Pichia pastoris strain under GAP promoter trigger increased KAR2 and PSA1-1 gene expression yielding enhanced extracellular productivity

Authors: Ana Lucía Herrera-Estala, José Antonio Fuentes-Garibay, Martha Guerrero-Olazarán, José María Viader-Salvadó

Journal: J Biotechnol

PubMed ID: 35618082

Doi: 10.1016/j.jbiotec.2022.05.010

Products & Services: GenParts™ DNA Fragments

Correction: The arginine deaminase system plays distinct roles in Borrelia burgdorferi and Borrelia hermsii

Authors: Crystal L Richards, Sandra J Raffel, Sébastien Bontemps-Gallo, Daniel P Dulebohn, Tessa C Herbert, Frank C Gherardini

Journal: PLoS Pathog

PubMed ID: 35536845

Doi: 10.1371/journal.ppat.1010549

Products & Services: Proteins, Expression, Isolation and Analysis

Enzymatically amplified linear dbDNA as a rapid and scalable solution to industrial lentiviral vector manufacturing

Authors: Maria Barreira, Claire Kerridge, Sara Jorda, Didrik Olofsson, Alexander Neumann, Helen Horton, Sarah Smith-Moore

Journal: Gene Ther

PubMed ID: 35606492

Doi: 10.1038/s41434-022-00343-4

Products & Services: Gene Synthesis

SEC is an antiangiogenic virulence factor that promotes endocarditis independent of superantigen activity

Authors: Kyle J Kinney, Sharon S Tang, Xiao-Jun Wu, Phuong M Tran, Nikhila S Bharadwaj, Katherine N Gibson-Corley, Ana N Forsythe, Katarina Kulhankova, Jenny E Gumperz, Wilmara Salgado-Pabón

Journal: Sci Adv

PubMed ID: 35544579

Doi: 10.1126/sciadv.abo1072

Products & Services: Gene Synthesis

Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes

Authors: Ayesa Syenina, Esther S Gan, Justin Z N Toh, Ruklanthi de Alwis, Lowell Z Lin, Christine Y L Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L E Wee, Dorothy H L Ng, Kuan Rong Chan, Jean X Y Sim, Shirin Kalimuddin, Eugenia Z Ong, Jenny G Low, Eng Eong Ooi

Journal: PLoS Biol

PubMed ID: 35639676

Doi: 10.1371/journal.pbio.3001643

High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA1

Authors: Maria Kuzikov, Jannis Woens, Andrea Zaliani, Julia Hambach, Thomas Eden, Boris Fehse, Bernhard Ellinger, Kristoffer Riecken

Journal: Biomed Pharmacother

PubMed ID: 35643072

Doi: 10.1016/j.biopha.2022.113104

Products & Services: Plasmid DNA Preparation

Scalable biological signal recording in mammalian cells using Cas12a base editors

Authors: Hannah R Kempton, Kasey S Love, Lucie Y Guo, Lei S Qi

Journal: Nat Chem Biol

PubMed ID: 35637351

Doi: 10.1038/s41589-022-01034-2

Products & Services: Proteins, Expression, Isolation and Analysis

Convergent Alterations of a Protein Hub Produce Divergent Effects within a Binding Site

Authors: Ali Imran, Brandon S Moyer, Dan Kalina, Thomas M Duncan, Kelsey J Moody, Aaron J Wolfe, Michael S Cosgrove, Liviu Movileanu

Journal: ACS Chem Biol

PubMed ID: 35613319

Doi: 10.1021/acschembio.2c00273

Products & Services: Proteins, Expression, Isolation and Analysis

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

Authors: Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E Ivanova, Kathryn M Stevens, Alex Montoya, S Sunidhi, Nicolas Lopez Carranza, Marcin J Skwark, Christian Speck

Journal: Nat Commun

PubMed ID: 35614055

Doi: 10.1038/s41467-022-30576-1

Products & Services: Mutant Libraries

Klotho-derived peptide 6 ameliorates diabetic kidney disease by targeting Wnt/b-catenin signaling

Authors: Xiaowen Chen , Huishi Tan , Jie Xu , Yuan Tian , Qian Yuan , Yangyang Zuo , Qiyan Chen , Xue Hong , Haiyan Fu , Fan Fan Hou , Lili Zhou , Youhua Liu

Journal: Kidney Int

PubMed ID: 35644285

Doi: 10.1016/j.kint.2022.04.028

Products & Services: Peptide Synthesis

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