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Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines.
Authors: Mehta NK,Pradhan RV,Soleimany AP,Moynihan KD,Rothschilds AM,Momin N,Rakhra K,Mata-Fink J,Bhatia SN,Wittrup KD,Irvine DJ
Journal: Nature biomedical engineering
PubMed ID: 32483299
Doi: 10.1038/s41551-020-0563-4
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Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment
Authors: Jing Sun, Zhen Zhuang, Jian Zheng, ..., Paul B. McCray, Jr., Stanley Perlman, Jincun Zhao
Journal: Cell
Doi: 10.1016/j.cell.2020.06.010
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Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro
Authors: Chulpanova DS, Solovyeva VV, James V, Arkhipova SS, Gomzikova MO, Garanina EE, Akhmetzyanova ER, Tazetdinova LG, Khaiboullina SF, Rizvanov AA
Journal: Bioengineering (Basel, Switzerland)
PubMed ID: 32560387
Doi: 10.3390/bioengineering7020059
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Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
Authors: Gupta V, Salim S, Hmila I, Vaikath NN, Sudhakaran IP, Ghanem SS, Majbour NK, Abdulla SA, Emara MM, Abdesselem HB, Lukacsovich T, Erskine D, El-Agnaf OMA
Journal: Scientific REPORTS
PubMed ID: 32424162
Doi: 10.1038/s41598-020-65035-8
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A role for actin flexibility in thin filament-mediated contractile regulation and myopathy
Authors: Viswanathan MC, Schmidt W, Franz P, Rynkiewicz MJ, Newhard CS, Madan A, Lehman W, Swank DM, Preller M, Cammarato A
Journal: Nature Communications
PubMed ID: 32415060
Doi: 10.1038/s41467-020-15922-5
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Diminution of Phagocytosed Micro/Nanoparticles by Tethering with Immunoregulatory CD200 Protein
Authors: Jun Zhang, Ching-An Peng
Journal: Sci Rep
PubMed ID: 32451434
Doi: 10.1038/s41598-020-65559-z
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Structural and Functional Adaptability of Sucrose and Lactose Permeases from Escherichia coli to the Membrane Lipid Composition
Authors: Vitrac H, Mallampalli VKPS, Azinas S, Dowhan W
Journal: Biochemistry
PubMed ID: 32363862
Doi: 10.1021/acs.biochem.0c00174
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BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway
Authors: Lan Lin, Xuliang Luo, Lin Wang, Fen Xu, Yuanqiao He, Qingyu Wang, Chunlei Yuan, Jing Xu, Liping Yan, Hua Hao
Journal: Int Immunopharmacol
PubMed ID: 32485356
Doi: 10.1016/j.intimp.2020.106625
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Ferritin-Displayed GLP-1 with Improved Pharmacological Activities and Pharmacokinetics
Authors: Su W, Tan H, Janowski R, Zhang W, Wang P, Zhang J, Zhai H, Li J, Niessing D, Sattler M, Zou P
Journal: Molecular Pharmaceutics
PubMed ID: 32243177
Doi: 10.1021/acs.molpharmaceut.0c00098
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Enhanced efficacy of a multi-epitope vaccine for type A and O foot‑and-mouth disease virus by fusing multiple epitopes with Mycobacterium tuberculosis heparin-binding hemagglutinin (HBHA), a novel TLR4 agonist
Authors: Lei Y, Shao J, Ma F, Lei C, Chang H, Zhang Y
Journal: Molecular immunology
PubMed ID: 32199211
Doi: 10.1016/j.molimm.2020.02.018
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