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RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease.
Authors: Gilham D, Wasiak S, Tsujikawa LM, Halliday C, Norek K, Patel RG, Kulikowski E, Johansson J, Sweeney M, Wong NC.
Journal: Atherosclerosis.
PubMed ID: 26868508
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Thrombopoietin/TGF‐β1 loop regulates megakaryocyte extracellular matrix component synthesis.
Authors: Abbonante V, Di Buduo CA, Gruppi C, Malara A, Gianelli U, Celesti G, Anselmo A, Laghi L, Vercellino M, Visai L, Iurlo A, Moratti R, Barosi G, Rosti V, Balduini A.
Journal: Stem Cells.
PubMed ID: 26748484
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Gastrin Decreases Na+, K+-ATPase Activity via a PI3 Kinase-and PKC-Dependent Pathway in Human Renal Proximal Tubule Cells.
Authors: Tianbing Liu, Prasad R. Konkalmatt, Yu Yang, Pedro A. Jose.
Journal: AJP-ENDOCRINOLOGY.
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Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo.
Authors: McLaughlin D,Coey CT,Yang WC,Drohat AC,Matunis MJ.
Journal: J Biol Chem.
PubMed ID: 26917720
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Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE).
Authors: Chandramouleeswaran PM, Shen D, Lee AJ, Benitez A, Dods K, Gambanga F, Wilkins BJ, Merves J,Noah Y, Toltzis S, Yearley JH, Spergel JM,Nakagawa H, Malefyt Rd, Muir AB,Wang ML.
Journal: PLoS One.
PubMed ID: 26992000
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Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting.
Authors: Kooijmans SA, Aleza CG, Roffler SR, van Solinge WW, Vader P, Schiffelers RM.
Journal: J Extracell Vesicles.
PubMed ID: 26979463
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Reciprocal signals between microglia and neurons regulate α-synuclein secretion by exophagy through a neuronal cJUN-N-terminal kinase-signaling axis.
Authors: Christensen DP, Ejlerskov P, Rasmussen I, Vilhardt F.
Journal: J Neuroinflammation.
PubMed ID: 26957005
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TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease.
Authors: ZhaoXiaobei,ChenXu-Qiao,HanEugene,HuYue,PaikPaul,DingZhiyong,OvermanJulia,LauAlice L,ShahmoradianSarah H,ChiuWah,ThompsonLeslie M,WuChengbiao,MobleyWilli
Journal: Proc. Natl. Acad. Sci. U.S.A.
PubMed ID: 27601642
Doi: 10.1073/pnas.1603020113
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Cytokine-like factor-1 (CLF-1): An essential facilitator of cardiotrophin-like cytokine: CNTFRα (CLC: CNTFRα) signalling and sorLA mediated turnover.
Authors: Larsen JV, Kristensen AM, Pallesen LT, Bauer J, Vægter CB, Nielsen MS, Madsen P, Petersen CM.
Journal: Mol Cell Biol.
PubMed ID: 26858303
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Immunisation with proteins expressed during chronic murine melioidosis provides enhanced protection against.
Authors: Champion OL, Gourlay LJ, Scott AE, Lassaux P, Conejero L, Perletti L, Hemsley C, Prior J, Bancroft G, Bolognesi M, Titball RW.
Journal: Vaccine.
PubMed ID: 26917010
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