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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 127/236 每页显示数量

Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania

Authors: Bhattacharya A1, Leprohon P1, Bigot S1,2, Padmanabhan PK1, Mukherjee A1, Roy G1, Gingras H1, Mestdagh A1, Papadopoulou B1,2, Ouellette M3,4.

Journal: Nat Commun.

PubMed ID: 31819054

Doi: 10.1038/s41467-019-13344-6

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Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway

Authors: Fenwick C1, Loredo-Varela JL#2, Joo V#1, Pellaton C1, Farina A1, Rajah N1, Esteves-Leuenberger L1, Decaillon T1, Suffiotti M1, Noto A1, Ohmiti K1, Gottardo R3, Weissenhorn W2, Pantaleo G4,5.

Journal: J Exp Med.

PubMed ID: 31123083

Doi: 10.1084/jem.20182359

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Maillard reaction with ribose， galacto-oligosaccharide or chitosan-oligosaccharide reduced the allergenicity of shrimp tropomyosin by inducing conformational changes.

Authors: FuLinglin，WangChong，WangJinbao，NiSaiqiao，WangY

Journal: Food Chem

PubMed ID: 30373009

Doi: 10.1016/j.foodchem.2018.09.068

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Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes.

Authors: KähäriLaura，Fair-MäkeläRuth，AuvinenKaisa，RantakariPia，JalkanenSirpa，IvaskaJohanna，SalmiM

Journal: J. Clin. Invest.

PubMed ID: 31232704

Doi: 10.1172/JCI125740

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Dynamic Contrast-Enhanced MRI of OATP Dysfunction in Diabetes.

Authors: Shuboni-MulliganDorela D，ParysMaciej，Blanco-FernandezBarbara，MallettChristiane L，SchnegelbergerRegina，TakadaMarilia，ChakravartyShatadru，HagenbuchBruno，ShapiroEr

Journal: Diabetes

PubMed ID: 30487262

Doi: 10.2337/db18-0525

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Correction: RanBP9 Overexpression Accelerates Loss of Pre and Postsynaptic Proteins in the APΔE9 Transgenic Mouse Brain.

Authors: WangHongjie，WangRuizhi，XuShaohua，LakshmanaMadepal

Journal: PLoS ONE

PubMed ID: 30995273

Doi: 10.1371/journal.pone.0215713

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GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation.

Authors: WitkosTomasz M，ChanWing Lee，JoensuuMerja，RhielManuel，PallisterEd，Thomas-OatesJane，MouldA Paul，MironovAlex A，BiotChristophe，GuerardelYann，MorelleWilly，UngarDaniel，WielandFelix T，JokitaloEija，TassabehjiMay，KornakUwe，LoweMa

Journal: Nat Commun

PubMed ID: 30631079

Doi: 10.1038/s41467-018-08044-6

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DoE to improve supercoiled p53-pDNA purification by O-phospho-l-tyrosine chromatography.

Authors: ValenteJ F A，SousaA，QueirozJ A，So

Journal: J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.

PubMed ID: 30597418

Doi: 10.1016/j.jchromb.2018.12.002

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A TIGIT-based chimeric co-stimulatory switch receptor improves T-cell anti-tumor function.

Authors: Hoogi Shiran，Eisenberg Vasyl，Mayer Shimrit，Shamul Astar，Barliya Tilda，Cohen Cyril

Journal: J Immunother Cancer

PubMed ID: 31500665

Doi: 10.1186/s40425-019-0721-y

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How prolonged expression of Hunchback， a temporal transcription factor， re-wires locomotor circuits.

Authors: Meng Julia L，Marshall Zarion D，Lobb-Rabe Meike，Heckscher Ell

Journal: Elife

PubMed ID: 31502540

Doi: 10.7554/eLife.46089

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