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Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes

Authors: Kaeli A Welsh, Derek L Bolhuis, Anneroos E Nederstigt, Joshua Boyer, Brenda R S Temple, Thomas Bonacci, Li Gu, Alban Ordureau, J Wade Harper, Joshua P Steimel, Qi Zhang, Michael J Emanuele, Joseph S Harrison, Nicholas G Brown

Journal: EMBO J

PubMed ID: 34942047

Doi: 10.15252/embj.2021108823

Products & Services: Proteins, Expression, Isolation and Analysis

MON-2, a Golgi protein, mediates autophagy-dependent longevity in

Authors: Yoonji Jung, Murat Artan, Nari Kim, Jeonghun Yeom, Ara B Hwang, Dae-Eun Jeong, Özlem Altintas, Keunhee Seo, Mihwa Seo, Dongyeop Lee, Wooseon Hwang, Yujin Lee, Jooyeon Sohn, Eun Ji E Kim, Sungeun Ju, Seong Kyu Han, Hyun-Jun Nam, Linnea Adams, Youngjae Ryu, Dong Jin Moon, Chanhee Kang, Joo-Yeon Yoo, Sang Ki Park, Chang Man Ha, Malene Hansen, Sanguk Kim, Cheolju Lee, Seung-Yeol Park, Seung-Jae V Lee

Journal: Sci Adv

PubMed ID: 34860542

Doi: 10.1126/sciadv.abj8156

Products & Services: Proteins, Expression, Isolation and Analysis

The protective effects of S14G-humanin (HNG) against streptozotocin (STZ)-induced cardiac dysfunction

Authors: Xiaopan Chen, Chuan Yun, Hailong Zheng, Xu Chen, Qianfei Han, Hua Pan, Yang Wang, Jianghua Zhong

Journal: Bioengineered

PubMed ID: 34506248

Doi: 10.1080/21655979.2021.1964894

Products & Services: Proteins, Expression, Isolation and Analysis

Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex

Authors: Luke F Pennington, Pascal Gasser, Silke Kleinboelting, Chensong Zhang, Georgios Skiniotis, Alexander Eggel, Theodore S Jardetzky

Journal: Nat Commun

PubMed ID: 34862384

Doi: 10.1038/s41467-021-27397-z

Products & Services: Proteins, Expression, Isolation and Analysis

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy

Authors: Emma L Lewis, Rong Xu, Jean-Christophe Beltra, Shin Foong Ngiow, Jordana Cohen, Rahul Telange, Alexander Crane, Deirdre Sawinski, E John Wherry, Paige M Porrett

Journal: J Exp Med

PubMed ID: 34882194

Doi: 10.1084/jem.20201599

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering CAR-T cells to activate small-molecule drugs in situ

Authors: Thomas J Gardner, J Peter Lee, Christopher M Bourne, Dinali Wijewarnasuriya, Nihar Kinarivala, Keifer G Kurtz, Broderick C Corless, Megan M Dacek, Aaron Y Chang, George Mo, Kha M Nguyen, Renier J Brentjens, Derek S Tan, David A Scheinberg

Journal: Nat Chem Biol

PubMed ID: 34969970

Doi: 10.1038/s41589-021-00932-1

Products & Services: Proteins, Expression, Isolation and Analysis

Enzymatic deamination of the epigenetic nucleoside N6-methyladenosine regulates gene expression

Authors: Zhuoran Jiang, Chao Wang, Zixin Wu, Kun Chen, Wei Yang, Hexiang Deng, Heng Song, Xiang Zhou

Journal: Nucleic Acids Res

PubMed ID: 34850126

Doi: 10.1093/nar/gkab1124

Products & Services: Proteins, Expression, Isolation and Analysis

Cryptic splicing events result in unexpected protein products from calpain-10 (CAPN10) cDNA

Authors: Yasuko Ono, Naoko Doi, Mayumi Shindo, Pablo Pánico, Ana María Salazar