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A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants

Authors: Laurie B Schenkel, Jennifer R Molina, Kerren K Swinger, Ryan Abo, Danielle J Blackwell, Alvin Z Lu, Anne E Cheung, W David Church, Kaiko Kunii, Kristy G Kuplast-Barr, Christina R Majer, Elena Minissale, Jan-Rung Mo, Mario Niepel, Christopher Reik, Yue Ren, Melissa M Vasbinder, Tim J Wigle, Victoria M Richon, Heike Keilhack, Kevin W Kuntz

Journal: Cell Chem Biol

PubMed ID: 33705687

Doi: 10.1016/j.chembiol.2021.02.010

Products & Services: Proteins, Expression, Isolation and Analysis

KCa31 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease

Authors: Fenglei Zheng, Yijing Tao, Jingjing Liu, Zhimin Geng, Ying Wang, Yujia Wang, Songling Fu, Wei Wang, Chunhong Xie, Yiying Zhang, Fangqi Gong

Journal: J Inflamm Res

PubMed ID: 33727847

Doi: 10.2147/JIR.S297131

Products & Services: Proteins, Expression, Isolation and Analysis

Adiponectin inhibits lipoplysaccharide-induced inflammation and promotes osteogenesis in hPDLCs

Authors: Huan-Huan Wu, Yuan Guo, Yin-Fei Pu, Zhi-Hui Tang

Journal: Biosci Rep

PubMed ID: 33616153

Doi: 10.1042/BSR20192668

Products & Services: Proteins, Expression, Isolation and Analysis

Mitochondrial functional resilience after TFAM ablation in the adult heart

Authors: Nasab Ghazal, Jessica N Peoples, Tahmina A Mohiuddin, Jennifer Q Kwong

Journal: Am J Physiol Cell Physiol

PubMed ID: 33760663

Doi: 10.1152/ajpcell.00508.2020

Products & Services: Proteins, Expression, Isolation and Analysis

Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation

Authors: Sébastien Coassolo, Guillaume Davidson, Luc Negroni, Giovanni Gambi, Sylvain Daujat, Christophe Romier, Irwin Davidson

Journal: Nat Commun

PubMed ID: 33741961

Doi: 10.1038/s41467-021-21960-4

Products & Services: Proteins, Expression, Isolation and Analysis

A thermo-responsive collagen-nanocellulose hydrogel for the growth of intestinal organoids

Authors: Rodrigo Curvello, Diana Alves, Helen E Abud, Gil Garnier

Journal: Mater Sci Eng C Mater Biol Appl

PubMed ID: 33947545

Doi: 10.1016/j.msec.2021.112051

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies

Authors: Renhong Yan, Ruoke Wang, Bin Ju, Jinfang Yu, Yuanyuan Zhang, Nan Liu, Jia Wang, Qi Zhang, Peng Chen, Bing Zhou, Yaning Li, Yaping Shen, Shuyuan Zhang, Long Tian, Yingying Guo, Lu Xia, Xinyue Zhong, Lin Cheng, Xiangyang Ge, Juanjuan Zhao, Hong-Wei Wang, Xinquan Wang, Zheng Zhang, Linqi Zhang, Qiang Zhou

Journal: Cell Res

PubMed ID: 33731853

Doi: 10.1038/s41422-021-00487-9

Products & Services: Proteins, Expression, Isolation and Analysis

The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism

Authors: Michelle Grace Acoba, Ebru S Selen Alpergin, Santosh Renuse, Lucía Fernández-Del-Río, Ya-Wen Lu, Oleh Khalimonchuk, Catherine F Clarke, Akhilesh Pandey, Michael J Wolfgang, Steven M Claypool

Journal: Cell Rep

PubMed ID: 33730581

Doi: 10.1016/j.celrep.2021.108869

Products & Services: Proteins, Expression, Isolation and Analysis

Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8 T Cell Tolerance Development

Authors: Martina Damo, D Scott Wilson, Elyse A Watkins, Jeffrey A Hubbell

Journal: Front Immunol

PubMed ID: 33746941

Doi: 10.3389/fimmu.2021.555095

Products & Services: Proteins, Expression, Isolation and Analysis

Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma

Authors: Yong Fu, Liang Ding, Xihu Yang, Zhuang Ding, Xiaofeng Huang, Lei Zhang, Sheng Chen, Qingang Hu, Yanhong Ni