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Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture.
Authors: Bjerregaard-Andersen Kaare,Johannesen Hedda,Abdel-Rahman Noha,Heggelund Julie Elisabeth,Hoås Helene Mykland,Abraha Fana,Bousquet Paula A,Høydahl Lene Støkken,Burschowsky Daniel,Rojas Gertrudis,Oscarson Stefan,Løset Geir Åge,Krengel
Journal: Sci Rep
PubMed ID: 30022069
Doi: 10.1038/s41598-018-28918-5
Products & Services: Recombinant Proteins   
The group VIA calcium-independent phospholipase A and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts.
Authors: Kuwata Hiroshi,Yuzurihara Chihiro,Kinoshita Natsumi,Taki Yuki,Ikegami Yuki,Washio Sana,Hirakawa Yushi,Yoda Emiko,Aiuchi Toshihiro,Itabe Hiroyuki,Nakatani Yoshihito,Hara Shun
Journal: FEBS J.
PubMed ID: 29637744
Doi: 10.1111/febs.14462
Products & Services: Recombinant Proteins   
Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reduction.
Authors: C?té Isabelle,Green Sara M,Morgan Drake,Carter Christy S,Tümer Nihal,Scarpace Phil
Journal: Can. J. Physiol. Pharmacol.
PubMed ID: 29131966
Doi: 10.1139/cjpp-2017-0440
Products & Services: Recombinant Proteins   
The in vitro effects of macrophages on the osteogenic capabilities of MC3T3-E1 cells encapsulated in a biomimetic poly(ethylene glycol) hydrogel.
Authors: Saleh Leila S,Carles-Carner Maria,Bryant Stephan
Journal: Acta Biomater
PubMed ID: 29505890
Doi: 10.1016/j.actbio.2018.02.026
Products & Services: Recombinant Proteins   
A GMCSF-Neuroantigen Tolerogenic Vaccine Elicits Systemic Lymphocytosis of CD4 CD25 FOXP3 Regulatory T Cells in Myelin-Specific TCR Transgenic Mice Contingent Upon Low-Efficiency T Cell Antigen Receptor Recognition.
Authors: Moorman Cody D,Curtis Alan D,Bastian Alexander G,Elliott Sarah E,Mannie Ma
Journal: Front Immunol
PubMed ID: 30687323
Doi: 10.3389/fimmu.2018.03119
Products & Services: Recombinant Proteins   
The anorectic effect of central PYY treatment in rainbow trout (Oncorhynchus mykiss) is associated with changes in mRNAs encoding neuropeptides and parameters related to fatty acid sensing and metabolism.
Authors: Velasco Cristina,Blanco Ayelén M,Unniappan Suraj,Soengas Jos
Journal: Gen. Comp. Endocrinol.
PubMed ID: 29940182
Doi: 10.1016/j.ygcen.2018.06.015
Products & Services: Recombinant Proteins   
TRPC5 Does Not Cause or Aggravate Glomerular Disease.
Authors: Wang Xuexiang,Dande Ranadheer R,Yu Hao,Samelko Beata,Miller Rachel E,Altintas Mehmet M,Reiser Jo
Journal: J. Am. Soc. Nephrol.
PubMed ID: 29061651
Doi: 10.1681/ASN.2017060682
Products & Services: Recombinant Proteins   
Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization.
Authors: Jiang Mei,Liu Xinghui,Zhang Denghai,Wang Ying,Hu Xiaoxia,Xu Fengxia,Jin Mingming,Cao Fanfan,Xu L
Journal: J Neuroinflammation
PubMed ID: 29540209
Doi: 10.1186/s12974-018-1124-6
Products & Services: Recombinant Proteins   
Brain Shuttle Antibody for Alzheimer's Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode.
Authors: Weber Felix,Bohrmann Bernd,Niewoehner Jens,Fischer Jens A A,Rueger Petra,Tiefenthaler Georg,Moelleken Joerg,Bujotzek Alexander,Brady Kevin,Singer Thomas,Ebeling Martin,Iglesias Antonio,Freskg?rd Per
Journal: Cell Rep
PubMed ID: 29298417
Doi: 10.1016/j.celrep.2017.12.019
Products & Services: Recombinant Proteins   
MultiBacMam Bimolecular Fluorescence Complementation (BiFC) tool-kit identifies new small-molecule inhibitors of the CDK5-p25 protein-protein interaction (PPI).
Authors: Bellón-Echeverría Itxaso,Carralot Jean-Philippe,Del Rosario Andrea Araujo,Kueng Stephanie,Mauser Harald,Schmid Georg,Thoma Ralf,Berger
Journal: Sci Rep
PubMed ID: 29572554
Doi: 10.1038/s41598-018-23516-x
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