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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib

Authors: Xuxing Shen, Chao Wu, Meng Lei, Qing Yan, Haoyang Zhang, Lina Zhang, Xueyuan Wang, Ye Yang, Jianyong Li, Yongqiang Zhu, Lijuan Chen

Journal: Cell Death Dis

PubMed ID: 33931582

Doi: 10.1038/s41419-021-03701-z

Products & Services: Recombinant Proteins

RNA-binding protein YBX1 promotes cell proliferation and invasiveness of nasopharyngeal carcinoma cells binding to AURKA mRNA

Authors: Yuanyuan Ban, Yixin Tan, Xiaoling Li, Xiayu Li, Zhaoyang Zeng, Wei Xiong, Guiyuan Li, Bo Xiang, Mei Yi

Journal: J Cancer

PubMed ID: 33976741

Doi: 10.7150/jca.56262

Products & Services: Recombinant Proteins

A role for PAK1 mediated phosphorylation of β-catenin Ser552 in the regulation of insulin secretion

Authors: Brie Sorrenson, Waruni C Dissanayake, Fengyun Hu, Kate L Lee, Peter R Shepherd

Journal: Biochem J

PubMed ID: 33605402

Doi: 10.1042/BCJ20200862

Products & Services: Recombinant Proteins

Identification and Characterization of Zika Virus NS5 Methyltransferase Inhibitors

Authors: Weibao Song, Hongjuan Zhang, Yu Zhang, Ying Chen, Yuan Lin, Yanxing Han, Jiandong Jiang

Journal: Front Cell Infect Microbiol

PubMed ID: 33898335

Doi: 10.3389/fcimb.2021.665379

Products & Services: Recombinant Proteins

Pathological Hyperinsulinemia and Hyperglycemia in the Impaired Glucose Tolerance Stage Mediate Endothelial Dysfunction Through miR-21, PTEN/AKT/eNOS, and MARK/ET-1 Pathways

Authors: Ran Liu, Shilin Guan, Zhongai Gao, Jingyu Wang, Jie Xu, Zhaohu Hao, Yi Zhang, Shaohua Yang, Zhenhong Guo, Juhong Yang, Hailin Shao, Baocheng Chang

Journal: Front Endocrinol (Lausanne)

PubMed ID: 33967958

Doi: 10.3389/fendo.2021.644159

Products & Services: Recombinant Proteins

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

Authors: Peter Gargalovic, Pancras Wong, Joelle Onorato, Heather Finlay, Tao Wang, Mujing Yan, Earl Crain, Stéphane St-Onge, Madeleine Héroux, Michel Bouvier, Carrie Xu, Xue-Qing Chen, Claudia Generaux, Michael Lawrence, Ruth Wexler, David Gordon

Journal: Circ Heart Fail

PubMed ID: 33663236

Doi: 10.1161/CIRCHEARTFAILURE.120.007351

Products & Services: Recombinant Proteins

By inhibiting ADCY5, miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture

Authors: Lei Wang, Junli Dong, Jun Ma, Qin Lu, Ben Shan, Tingting Han, Peng Xie, Xiaohua Zuo

Journal: Biochem Biophys Res Commun

PubMed ID: 33684620

Doi: 10.1016/j.bbrc.2021.02.118

Products & Services: Recombinant Proteins

Inhibition of P110α and P110δ catalytic subunits of PI3 kinase reverses impaired arterial healing after injury in hypercholesterolemic male mice

Authors: Pinaki Chaudhuri, Andrew H Smith, Linda M Graham, Michael A Rosenbaum

Journal: Am J Physiol Cell Physiol

PubMed ID: 33689479

Doi: 10.1152/ajpcell.00600.2020

Products & Services: Recombinant Proteins

Obtusifolin, an Anthraquinone Extracted from (L) HSIrwin & Barneby, Reduces Inflammation in a Mouse Osteoarthritis Model

Authors: Jiho Nam, Dong-Won Seol, Choong-Gu Lee, Gabbine Wee, Siyoung Yang, Cheol-Ho Pan

Journal: Pharmaceuticals (Basel)

PubMed ID: 33802005

Doi: 10.3390/ph14030249

Products & Services: Recombinant Proteins

Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy

Authors: Chenglong Liu, Feilong Zhou, Ziqin Yan, Lian Shen, Xichen Zhang, Fenglian He, Heng Wang, Xiaojie Lu, Ker Yu, Yujun Zhao, Di Zhu

Journal: Br J Pharmacol

PubMed ID: 33768523

Doi: 10.1111/bph.15457

Products & Services: Recombinant Proteins

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