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Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells.
Authors: Tong Zhixiang,Martyn Keir,Yang Andy,Yin Xiaolei,Mead Benjamin E,Joshi Nitin,Sherman Nicholas E,Langer Robert S,Karp Jeffr
Journal: Biomaterials
PubMed ID: 29120819
Doi: 10.1016/j.biomaterials.2017.10.038
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Dictyostelium Erk2 is an atypical MAPK required for chemotaxis.
Authors: Schwebs David J,Pan Miao,Adhikari Nirakar,Kuburich Nick A,Jin Tian,Hadwiger Jeffr
Journal: Cell. Signal.
PubMed ID: 29551366
Doi: 10.1016/j.cellsig.2018.03.006
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Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses.
Authors: Park Simone L,Zaid Ali,Hor Jyh Liang,Christo Susan N,Prier Julia E,Davies Brooke,Alexandre Yannick O,Gregory Julia L,Russell Tiffany A,Gebhardt Thomas,Carbone Francis R,Tscharke David C,Heath William R,Mueller Scott N,Mackay Lau
Journal: Nat. Immunol.
PubMed ID: 29311695
Doi: 10.1038/s41590-017-0027-5
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Safety and efficacy of anti-PD-L1 therapy in the woodchuck model of HBV infection.
Authors: BalsitisScott,GaliVolodymyr,MasonPamela J,ChaniewskiSusan,LevineSteven M,WichroskiMichael J,FeulnerMichael,SongYunling,GranaldiKaren,LoyJames K,ThompsonChris M,LesniakJacob A,BrockusCatherine,KishnaniNarendra,MenneStephan,CockettMark I,IyerRenuka,MasonStephen W,TenneyDani
Journal: PLoS ONE
PubMed ID: 29444087
Doi: 10.1371/journal.pone.0190058
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Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design.
Authors: ShawSubrata,BianZhiguo,ZhaoBin,TarrJames C,VeerasamyNagarathanam,JeonKyu Ok,BelmarJohannes,ArnoldAllison L,FogartyStuart A,PerryEvan,SensintaffarJohn L,CamperDeMarco V,RossaneseOlivia W,LeeTaekyu,OlejniczakEdward T,FesikSteph
Journal: J. Med. Chem.
PubMed ID: 29323899
Doi: 10.1021/acs.jmedchem.7b01155
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An F-type lectin domain directs the activity of Streptosporangium roseum alpha-L-fucosidase.
Authors: BishnoiRitika,MahajanSonal,RamyaT
Journal: Glycobiology
PubMed ID: 30169639
Doi: 10.1093/glycob/cwy079
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TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.
Authors: DeshaiesJade-Emmanuelle,ShkretaLulzim,MoszczynskiAlexander J,SidibéHadjara,SemmlerSabrina,FouillenAurélien,BennettEstelle R,BekensteinUriya,DestroismaisonsLaurie,ToutantJohanne,DelmotteQuentin,VolkeningKathryn,StabileStéphanie,AulasAnaïs,KhalfallahYousra,SoreqHermona,NanciAntonio,StrongMichael J,ChabotBenoit,Vande VeldeChris
Journal: Brain
PubMed ID: 29562314
Doi: 10.1093/brain/awy062
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A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.
Authors: ChitiproluManeka,JagowChantal,TremblayVeronique,Bondy-ChorneyEmma,ParisGeneviève,SavardAlexandre,PalidworGareth,BarryFrancesca A,ZinmanLorne,KeithJulia,RogaevaEkaterina,RobertsonJanice,Lavallée-AdamMathieu,WoulfeJohn,CoutureJean-François,CôtéJocelyn,GibbingsDer
Journal: Nat Commun
PubMed ID: 30022074
Doi: 10.1038/s41467-018-05273-7
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The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding.
Authors: MadiganJames P,HouFeng,YeLinlei,HuJicheng,DongAiping,TempelWolfram,YoheMarielle E,RandazzoPaul A,JenkinsLisa M Miller,GottesmanMichael M,TongYu
Journal: J. Biol. Chem.
PubMed ID: 30143532
Doi: 10.1074/jbc.RA118.003525
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Improving the Activity of Trp-Rich Antimicrobial Peptides by Arg/Lys Substitutions and Changing the Length of Cationic Residues.
Authors: AriasMauricio,PigaKathlyn B,HyndmanM Eric,VogelHa
Journal: Biomolecules
PubMed ID: 29671805
Doi: 10.3390/biom8020019
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