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A novel point mutation (L70P) inactivates poliovirus 3C protease.
Authors: Uma M, Hegde SR, Rao PP, Nagalekshmi K, Gauthami S, Kumar D, Hegde NR.
Journal: Acta Virol
PubMed ID: 29521105
Doi: 10.4149/av_2018_108
Products & Services: Peptide Synthesis   
A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages.
Authors: Schafer C,, Dambrauskas N,, Steel RW,, Carbonetti S, Chuenchob V, Flannery EL,, Vigdorovich V,, Oliver BG,, Roobsoong W, Maher SP, Kyle D, Sattabongkot J, Kappe SHI,,, Mikolajczak SA,, Sather DN,,.
Journal: Malar J
PubMed ID: 30333026
Doi: 10.1186/s12936-018-2519-7
Products & Services: Peptide Synthesis   
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.
Authors: Park JB, Kim YH, Yoo Y, Kim J, Jun SH,, Cho JW, El Qaidi S, Walpole S, Monaco S, García-García AA, Wu M, Hays MP, Hurtado-Guerrero R,, Angulo J, Hardwidge PR, Shin JS,, Cho HS.
Journal: Nat Commun
PubMed ID: 30327479
Doi: 10.1038/s41467-018-06680-6
Products & Services: Peptide Synthesis   
A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia.
Authors: Ramsey HE, Fischer MA, Lee T,, Gorska AE, Arrate MP, Fuller L, Boyd KL, Strickland SA,, Sensintaffar J, Hogdal LJ, Ayers GD,,, Olejniczak ET,, Fesik SW,,, Savona MR,.
Journal: Cancer Discov
PubMed ID: 30185627
Doi: 10.1158/2159-8290.CD-18-0140
Products & Services: Peptide Synthesis   
Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte.
Authors: Marapana DS,, Dagley LF,, Sandow JJ,, Nebl T,, Triglia T, Pasternak M,, Dickerman BK, Crabb BS, Gilson PR, Webb AI,, Boddey JA,, Cowman AF,.
Journal: Nat Microbiol
PubMed ID: 30127496
Doi: 10.1038/s41564-018-0219-2
Products & Services: Peptide Synthesis   
Synthetic matrix enhances transplanted satellite cell engraftment in dystrophic and aged skeletal muscle with comorbid trauma.
Authors: Han WM,, Anderson SE,, Mohiuddin M,, Barros D,,,,, Nakhai SA,, Shin E,, Amaral IF,,, Pêgo AP,,,, García AJ,, Jang YC,,.
Journal: Sci Adv
PubMed ID: 30116776
Doi: 10.1126/sciadv.aar4008
Products & Services: Peptide Synthesis   
Aliphatic Azides as Selective Cysteine Labeling Reagents for Integral Membrane Proteins.
Authors: Szymanski D, Papanastasiou M, Pandarinathan L, Zvonok N, Janero DR, Pavlopoulos S, Vouros P, Makriyannis A.
Journal: J Med Chem
PubMed ID: 30444608
Doi: 10.1021/acs.jmedchem.8b01302
Products & Services: Peptide Synthesis   
Deprotonation of a Single Amino Acid Residue Induces Significant Stability in an α-Helical Heteropeptide.
Authors: Jas GS, Kuczera K.
Journal: J Phys Chem B
PubMed ID: 30339390
Doi: 10.1021/acs.jpcb.8b07418
Products & Services: Peptide Synthesis   
Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity.
Authors: Davenport AJ,, Cross RS,,, Watson KA,, Liao Y,, Shi W,, Prince HM,, Beavis PA,, Trapani JA,, Kershaw MH,, Ritchie DS,, Darcy PK,, Neeson PJ,, Jenkins MR,,,,.
Journal: Proc Natl Acad Sci U S A
PubMed ID: 29440406
Doi: 10.1073/pnas.1716266115
Products & Services: Peptide Synthesis   
Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Authors: Ma L, Chin YKY, Dekan Z, Herzig V, Chow CY, Heighway J, Lam SW, Guillemin GJ, Alewood PF, King GF.
Journal: Biochem Pharmacol
PubMed ID: 30149017
Doi: 10.1016/j.bcp.2018.08.038
Products & Services: Peptide Synthesis   

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