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页码: 2/788 每页显示数量
Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules
Authors: Christopher M. Hickey, Katherine M. Digianantonio, Kurt Zimmermann  , Alicia Harbin, Connor Quinn, Avani Patel, Peter Gareiss  , Amanda Chapman1 , Bernadette Tiberi1,2, Jennifer Dobrodziej1,3, John Corradi1 , Angela M. Cacace1 , David R. Langley & Miklós Békés
Journal: NATURE STRUCTURAL & MOLECULAR BIOLOGY
Doi: 10.1038/s41594-023-01146-w
Products & Services: Peptide Synthesis   Gene Synthesis   
Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate
Authors: Liyang Du , Qinwei Zhu & Zhonghui Lin
Journal: The EMBO Journal
Doi: 10.1038/s44318-023-00017-w
Products & Services: Gene Synthesis   
Biguanide chitosan microneedles with cell-free DNA scavenging ability for psoriasis therapy
Authors: Zihao Liu , Yu Wang , Yuhan Zhang , Liufu Hu , Bozhi Chen , Yang Li , Xindong Guo , Bingran Yu , Fu-Jian Xu
Journal: Bioactive Materials
Doi: 10.1016/j.bioactmat.2023.11.015
Products & Services: Gene Synthesis   
Plant-based meat analogues enhance the gastrointestinal motility function and appetite of mice by specific volatile compounds and peptides
Authors: Yunting Xie, Linlin Cai, Mengzhen Ding, Kai Shan, Di Zhao, Guanghong Zhou, Chunbao Li
Journal: Food Research International
Doi: 10.1016/j.foodres.2023.113551
Products & Services: Gene Synthesis   
Covalent PROTAC design method based on a sulfonyl pyridone probe
Authors: Qinhong Luo , Yaqi Wang , Zhanfeng Hou , Huiting Liang , Licheng Tu , Yun Xing , Chuan Wan , Jianbo Liu , Rui Wang , Lizhi Zhu , Wei Han , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li
Journal: Chem Commun (Camb) .
PubMed ID: 38054347
Doi: 10.1039/d3cc05127g
Products & Services: Gene Synthesis   
Discrimination of Disaccharide Isomers of Different Glycosidic Linkages Using a Modified MspA Nanopore
Authors: Shanyu Zhang , Zhenyuan Cao , Pingping Fan , Wen Sun , Yunqi Xiao , Panke Zhang , Yuqin Wang , Shuo Huang
Journal: Angew Chem Int Ed Engl .
PubMed ID: 38116834
Doi: 10.1002/anie.202316766
Products & Services: Gene Synthesis   
Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region
Authors: Qinhong Luo , Yue Ma , Huiting Liang , Yuan Feng , Na Liu, Chenshan Lian , Lizhi Zhu , Yuxin Ye , Zhihong Liu , Zhanfeng Hou , Sijin Chen , Yaqi Wang , Chuan Dai , Chunli Song , Min Zhang , Zhipeng He , Yun Xing , Wanjin Zhong , Shuiming Li , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li
Journal: J Med Chem .
PubMed ID: 37922441
Doi: 10.1021/acs.jmedchem.3c01549
Products & Services: Gene Synthesis   
A Subunit Vaccine Candidate Composed of Mpox Virus A29L, M1R, A35R, and B6R Elicits Robust Immune Response in Mice
Authors: Xuetao Yang , Xidan Yang , Shouwen Du , Congxia Hu , Xiu Yang , Xingyun Wang , Xing Hu , Nino Rcheulishvili , Peng George Wang and Jihui Lin
Journal: Vaccines.
Doi: 10.3390/vaccines11091420
Products & Services: Gene Synthesis   
Self−Assembling Nanovaccine Fused with Flagellin Enhances Protective Effect against Foot−and−Mouth Disease Virus
Authors: Chenchen Pei , Hu Dong , Zhidong Teng , Sumin Wei , Yun Zhang , Shuanghui Yin , Jianli Tang , Shiqi Sun and Huichen Guo
Journal: Vaccines
Doi: 10.3390/vaccines11111675
Products & Services: Gene Synthesis   
Development and characterization of anti-IL-5 monoclonal antibody Fab fragment for blocking IL-5/IL-5Rα binding
Authors: Shijie Li , Shijie Wang , Eric Fordjour , Yaoji Liang , Xuelian Wang , Yonghao Ye , Zhonghu Bai , Yankun Yang , Yongqi Chen
Journal: International Immunopharmacology
Doi: doi.org/10.1016/j.intimp.2023.111032
Products & Services: Gene Synthesis   Peptide Synthesis   
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