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Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation
Authors: Eisho Kanemitsu, Xiangdong Zhao, Keiko Iwaisako, Asuka Inoue, Akihide Takeuchi, Shintaro Yagi, Hidetoshi Masumoto, Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Junken Aoki, Etsuro Hatano, Shinji Uemoto, Masatoshi Hagiwara
Journal: Transl Res
PubMed ID: 36347491
Doi: 10.1016/j.trsl.2022.11.003
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Recombinant Vaccinia Virus Expressing Apical Membrane Antigen 1 or Microneme Protein Enhances Protection against Infection in Mice
Authors: Min-Ju Kim, Ki-Back Chu, Su-Hwa Lee, Hae-Ji Kang, Keon-Woong Yoon, Md Atique Ahmed, Fu-Shi Quan
Journal: Trop Med Infect Dis
PubMed ID: 36355892
Doi: 10.3390/tropicalmed7110350
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TMBIM5 is the Ca /H antiporter of mammalian mitochondria
Authors: Shane Austin, Ronald Mekis, Sami E M Mohammed, Mariafrancesca Scalise, Wen-An Wang, Michele Galluccio, Christina Pfeiffer, Tamara Borovec, Katja Parapatics, Dijana Vitko, Nora Dinhopl, Nicolas Demaurex, Keiryn L Bennett, Cesare Indiveri, Karin Nowikovsky
Journal: EMBO Rep
PubMed ID: 36321428
Doi: 10.15252/embr.202254978
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Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling
Authors: Bo Yu, Shiyu Luo, Yuhan Ding, Zijie Gong, Ting Nie
Journal: AMB Express
PubMed ID: 36370155
Doi: 10.1186/s13568-022-01489-5
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Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease
Authors: Hangchen Hu, Qian Wang, Haixia Su, Qiang Shao, Wenfeng Zhao, Guofeng Chen, Minjun Li, Yechun Xu
Journal: Angew Chem Int Ed Engl
PubMed ID: 36308706
Doi: 10.1002/anie.202212378
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A broadly protective vaccine against cutaneous human papillomaviruses
Authors: Filipe Colaco Mariz, Kathrin Balz, Manuela Dittrich, Yueru Zhang, Fan Yang, Xueer Zhao, Angelo Bolchi, Simone Ottonello, Martin Müller
Journal: npj Vaccines
PubMed ID: 36216845
Doi: 10.1038/s41541-022-00539-0
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Combating the SARS-CoV-2 Omicron (BA1) and BA2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Authors: Yingdan Wang, Xiang Zhang, Yunping Ma, Yanqun Wang, Wuqiang Zhan, Qinwen Zheng, Meng Zhang, Ping Ji, Mei Liu, Qianying Liu, Tingting Sun, Tongyu Zhu, Yumei Wen, Lei Sun, Jincun Zhao, Fan Wu, Zhenguo Chen, Jinghe Huang
Journal: Cell Discov
PubMed ID: 36207299
Doi: 10.1038/s41421-022-00463-6
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Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H αβ tetramer
Authors: Abhinandan V Murthy, Ramita Sulu, Andrey Lebedev, Antti M Salo, Kati Korhonen, Rajaram Venkatesan, Hongmin Tu, Ulrich Bergmann, Janne Jänis, Mikko Laitaoja, Lloyd W Ruddock, Johanna Myllyharju, M Kristian Koski, Rik K Wierenga
Journal: J Biol Chem
PubMed ID: 36265586
Doi: 10.1016/j.jbc.2022.102614
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CD8+ T cell clonotypes from prior SARS-CoV-2 infection predominate during the cellular immune response to mRNA vaccination
Authors: Emily S Ford, Koshlan Mayer-Blackwell, Lichen Jing, Anton M Sholukh, Russell St Germain, Emily L Bossard, Hong Xie, Thomas H Pulliam, Saumya Jani, Stacy Selke, Carlissa J Burrow, Christopher L McClurkan, Anna Wald, Michael R Holbrook, Brett Eaton, Elizabeth Eudy, Michael Murphy, Elena Postnikova, Harlan S Robins, Rebecca Elyanow, Rachel M Gittelman, Matyas Ecsedi, Elise Wilcox, Aude G Chapuis, Andrew Fiore-Gartland, David M Koelle
Journal: Res Sq
PubMed ID: 36263073
Doi: 10.21203/rs.3.rs-2146712/v1
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A tunable metabolic valve for precise growth control and increased product formation in Pseudomonas putida
Authors: Christos Batianis, Rik P van Rosmalen, Monika Major, Cheyenne van Ee, Alexandros Kasiotakis, Ruud A Weusthuis, Vitor A P Martins Dos Santos
Journal: Metab Eng
PubMed ID: 36244546
Doi: 10.1016/j.ymben.2022.10.002
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