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The mitochondrial single-stranded DNA binding protein from S cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers
Authors: Singh SP, Kukshal V, De Bona P, Antony E, Galletto R.
Journal: Nucleic Acids Res
PubMed ID: 29931186
Doi: 10.1093/nar/gky530
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Vaccination of sows with a dendritic cell-targeted porcine epidemic diarrhea virus S1 protein-based candidate vaccine reduced viral shedding but exacerbated gross pathological lesions in suckling neonatal piglets.
Authors: Subramaniam S, Yugo DM, Heffron CL, Rogers AJ, Sooryanarain H, LeRoith T, Overend C,, Cao D, Meng XJ.
Journal: J Gen Virol
PubMed ID: 29300158
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Identification of MazF Homologue in Legionella pneumophila Which Cleaves RNA at the AACU Sequence.
Authors: Shaku M, Park JH, Inouye M, Yamaguchi Y,.
Journal: J Mol Microbiol Biotechnol
PubMed ID: 30893701
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A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling.
Authors: Soto-VelasquezMonica,HayesMichael P,AlpsoyAktan,DykhuizenEmily C,WattsV
Journal: Mol. Pharmacol.
PubMed ID: 29950405
Doi: 10.1124/mol.118.111849
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CD95/Fas ligand mRNA is toxic to cells.
Authors: PutzbachWill,Haluck-KangasAshley,GaoQuan Q,SarshadAishe A,BartomElizabeth T,StultsAustin,QadirAbdul S,HafnerMarkus,PeterMarc
Journal: Elife
PubMed ID: 30324908
Doi: 10.7554/eLife.38621
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The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis.
Authors: PackianathanCharles,KandaveluPalani,RosenBar
Journal: Biochemistry
PubMed ID: 29894638
Doi: 10.1021/acs.biochem.8b00457
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TLR Crosstalk Activates LRP1 to Recruit Rab8a and PI3Kγ for Suppression of Inflammatory Responses.
Authors: Luo L, Wall AA, Tong SJ, Hung Y, Xiao Z, Tarique AA, Sly PD, Fantino E, Marzolo MP, Stow JL.
Journal: Cell Rep
PubMed ID: 30208326
Doi: 10.1016/j.celrep.2018.08.028
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A Nanostructured Lipid Carrier for Delivery of a Replicating Viral RNA Provides Single, Low-Dose Protection against Zika.
Authors: Erasmus JH, Khandhar AP, Guderian J, Granger B, Archer J, Archer M, Gage E, Fuerte-Stone J, Larson E, Lin S, Kramer R, Coler RN, Fox CB, Stinchcomb DT, Reed SG, Van Hoeven N.
Journal: Mol Ther
PubMed ID: 30078765
Doi: 10.1016/j.ymthe.2018.07.010
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Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA.
Authors: Suno R, Kimura KT, Nakane T, Yamashita K, Wang J, Fujiwara T, Yamanaka Y, Im D, Horita S, Tsujimoto H, Tawaramoto MS, Hirokawa T, Nango E, Tono K, Kameshima T, Hatsui T, Joti Y, Yabashi M, Shimamoto K, Yamamoto M, Rosenbaum DM, Iwata S, Shimamura T, Kobayashi T.
Journal: Structure
PubMed ID: 29225076
Doi: 10.1016/j.str.2017.11.005
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